159 Result(s)
within
Kui **a
Biomedicine, general
-
Article
Controllable synthesis of one-dimensional silicon nanostructures based on the dual effects of electro-deoxidation and the Kirkendall effect
In this study, we successfully synthesized silicon nanotubes (Si-NTs) and silicon nanowires (Si-NWs) in a controllable manner using a catalyst- and template-free method through the direct electrolysis of SiO2 in ...
-
Article
Sulfonated carbon dots modified IrO2 nanosheet as durable and high-efficient electrocatalyst for boosting acidic oxygen evolution reaction
Oxygen evolution reaction (OER) plays a crucial role in develo** energy conversion and adjusting electronic structure of the electrocatalysts can effectively improve the catalytic activity and stability. How...
-
Article
Formation of ZnSe magic-size clusters displaying optical absorption doublets from prenucleation clusters
The formation pathway of colloidal semiconductor ZnSe magic-size clusters (MSCs) in a reaction that display an optical absorption doublet remains poorly understood. The reaction of Zn(OAc)2/OLA (made from zinc ac...
-
Article
Open AccessAssociations of neighborhood sociodemographic environment with mortality and circulating metabolites among low-income black and white adults living in the southeastern United States
Residing in a disadvantaged neighborhood has been linked to increased mortality. However, the impact of residential segregation and social vulnerability on cause-specific mortality is understudied. Additionall...
-
Article
An ultra-sensitive biosensor for circulating microRNA detection with Fe single-atom enhanced cathodic luminol-O2 electrochemiluminescence
Circulating microRNAs (miRNAs) play a pivotal role in the occurrence and development of acute myocardial infarction (AMI), and precise detection of them holds significant clinical implications. The development...
-
Article
Open AccessStructure-guided discovery of highly efficient cytidine deaminases with sequence-context independence
The applicability of cytosine base editors is hindered by their dependence on sequence context and by off-target effects. Here, by using AlphaFold2 to predict the three-dimensional structure of 1,483 cytidine ...
-
Article
An effective cross-scenario remote heart rate estimation network based on global–local information and video transformer
Remote photoplethysmography (rPPG) technology is a non-contact physiological signal measurement method, characterized by non-invasiveness and ease of use. It has broad application potential in medical health, ...
-
Article
Divergent age-associated and metabolism-associated gut microbiome signatures modulate cardiovascular disease risk
Insight into associations between the gut microbiome with metabolism and aging is crucial for tailoring interventions to promote healthy longevity. In a discovery cohort of 10,207 individuals aged 40–93 years,...
-
Article
Senaparib as first-line maintenance therapy in advanced ovarian cancer: a randomized phase 3 trial
Poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors as maintenance therapy after first-line chemotherapy have improved progression-free survival in women with advanced ovarian cancer; however, not ...
-
Article
Open AccessPragmatic nationwide master observational trial based on genomic alterations in advanced solid tumors: KOrean Precision Medicine Networking Group Study of MOlecular profiling guided therapy based on genomic alterations in advanced Solid tumors (KOSMOS)-II study protocol KCSG AL-22–09
Next-generation sequencing (NGS) has been introduced to many Korean institutions to support molecular diagnostics in cancer since 2017, when it became eligible for reimbursement by the National Health Insuranc...
-
Article
Open AccessPredictive Value of 5-Methoxytryptophan on Long-Term Clinical Outcome after PCI in Patients with Acute Myocardial Infarction-a Prospective Cohort Study
In recent years, 5-Methoxytryptophan (5-MTP) has been identified as an endothelial factor with vaso-protective and anti-inflammatory properties.
-
Article
Highly selective electrosynthesis of 3,4-dihydroisoquinoline accompanied with hydrogen production over three-dimensional hollow CoNi-based microarray electrocatalysts
Electrocatalytic oxidation reaction of biomass-based derivatives is an excellent candidate to replace water oxidation for obtaining both value-added products and hydrogen (H2), but the exploration of competent el...
-
Article
Recent advances and applications of single atom catalysts based electrochemical sensors
Single atom catalysts (SACs) have attracted considerable attention due to their unique structures and excellent catalytic performance, especially in the area of catalysis science and energy conversion and stor...
-
Article
Hepatitis B virus core protein stabilizes RANGAP1 to upregulate KDM2A and facilitate hepatocarcinogenesis
As a vital component of the hepatitis B virus (HBV) nucleocapsid, HBV core protein (HBC) contributes to hepatocarcinogenesis. Here, we aimed to assess the effects of RANGAP1 and KDM2A on tumorigenesis induced ...
-
Article
Open AccessA single-cell atlas enables map** of homeostatic cellular shifts in the adult human breast
Here we use single-cell RNA sequencing to compile a human breast cell atlas assembled from 55 donors that had undergone reduction mammoplasties or risk reduction mastectomies. From more than 800,000 cells we i...
-
Article
Open AccessTumor burden score and carcinoembryonic antigen predict outcomes in patients with intrahepatic cholangiocarcinoma following liver resection: a multi‑institutional analysis
The prognostic significance of tumor burden score (TBS) in relation to carcinoembryonic antigen (CEA) has not been investigated among patients undergoing hepatectomy for intrahepatic cholangiocarcinoma (ICC). ...
-
Article
Protective effects of curcumin on desipramine-induced islet β-cell damage via AKAP150/PKA/PP2B complex
Tricyclic antidepressants (TCAs) are widely used to treat depression and anxiety-related mood disorders. But evidence shows that TCAs elevate blood glucose levels and inhibit insulin secretion, suggesting that...
-
Article
Open AccessEarly tirofiban versus heparin for bridging dual antiplatelet therapy in patients undergoing coronary endarterectomy combined with coronary artery bypass grafting: a multicenter randomized controlled trial protocol (the THACE-CABG trial)
For complete revascularization, patients with diffuse coronary artery disease should have a coronary endarterectomy and a coronary artery bypass graft (CE-CABG). Sadly, CE can lead to a lack of endothelium, wh...
-
Article
Open AccessNanomaterial-encapsulated STING agonists for immune modulation in cancer therapy
The cGAS-STING signaling pathway has emerged as a critical mediator of innate immune responses, playing a crucial role in improving antitumor immunity through immune effector responses. Targeting the cGAS-STIN...
-
Article
Open AccessA compendium of genetic regulatory effects across pig tissues
The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock, which is essential for linking genetic polymorphisms...
