232 Result(s)
within
Kui **a
Biochemistry, general
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Article
Selenium Status Associates with Thyroid Hormone and Thyroid Dysfunction in Older Chinese Adults
Selenium (Se) is physiologically essential for thyroid function. However, epidemiological studies on the association between Se status and thyroid function are limited and the results are inconsistent. Therefo...
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Article
Retraction Note: Curcumin amends Ca2 + dysregulation in microglia by suppressing the activation of P2 × 7 receptor
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Article
Mechanism of Peptide Self-assembly and Its Study in Biomedicine
The development of peptide-based materials is one of the most challenging aspects of biomaterials research in recent years. The assembly of peptides is mainly controlled by forces such as hydrogen bonding, hyd...
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Open AccessAssessment of monoclonal antibody glycosylation: a comparative study using HRMS, NMR, and HILIC-FLD
Monoclonal antibodies (mAbs) represent the largest class of therapeutic protein drug products. mAb glycosylation produces a heterogeneous, analytically challenging distribution of glycoforms that typically sho...
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Open AccessMETTL3-mediated deficiency of lncRNA HAR1A drives non-small cell lung cancer growth and metastasis by promoting ANXA2 stabilization
We previously reported lncRNA HAR1A as a tumor suppressor in non-small cell lung cancer (NSCLC). However, the delicate working mechanisms of this lncRNA remain obscure. Herein, we demonstrated that the ectopic ex...
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Article
Interaction of Cecropin A (1–7) Analogs with DNA Analyzed by Multi-spectroscopic Methods
Cecropin A (1–7) is a cationic antimicrobial peptide which contain lots of basic amino acids. To understand the effect of basic amino acids on cecropin A (1–7), analogues CA2, CA3 and CA4 which have more argin...
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Comprehensive pan-cancer analysis reveals SIRT5 is a predictive biomarker for prognosis and immunotherapy response
Sirtuin 5 (SIRT5) is a promising therapeutic target involved in regulating multiple metabolic pathways in cells and organisms. The role of SIRT5 in cancer is currently unclear, and a comprehensive systematic p...
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Article
Correction: THUMPD3-AS1 facilitates cell growth and aggressiveness by the miR-218-5p/SKAP1 axis in colorectal cancer
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Article
Zinc Oxide Nanoparticles Trigger Autophagy in the Human Multiple Myeloma Cell Line RPMI8226: an In Vitro Study
Multiple myeloma (MM) is a malignant clonal proliferative plasma cell tumor. Zinc oxide nanoparticles (ZnO NPs) are used for antibacterial and antitumor applications in the biomedical field. This study investi...
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Article
Profiling and Bioinformatics Analyses of Hypoxia-Induced Differential Expression of Long Non-coding RNA in Glioblastoma Multiforme Cells
Hypoxic microenvironments are intricately linked to malignant characteristics of glioblastoma multiforme (GBM). Long non-coding ribonucleic acids (lncRNAs) have been reported to be involved in the progression ...
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Article
Open AccessImmune landscape and redox imbalance during neurological disorders in COVID-19
The outbreak of Coronavirus Disease 2019 (COVID-19) has prompted the scientific community to explore potential treatments or vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the v...
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Effects of Molybdenosis on Antioxidant Capacity in Endangered Przewalski’s Gazelles in the Qinghai Lake National Nature Reserve in the Northwestern China
The purpose of this study is to investigate the effects of molybdenosis on antioxidant capacity in endangered Przewalski’s gazelles (Procapra przewalskii) in the animal rescue center in the Qinghai Lake National ...
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Article
Metformin attenuates sevoflurane-induced neurogenesis damage and cognitive impairment: involvement of the Nrf2/G6PD pathway
Anesthetics such as sevoflurane are commonly administered to infants and children. However, the possible neurotoxicity caused by prolonged or repetitive exposure to it should be a concern. The neuroprotective ...
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Article
Selective CDK9 knockdown sensitizes TRAIL response by suppression of antiapoptotic factors and NF-kappaB pathway
The aberrantly up-regulated CDK9 can be targeted for cancer therapy. The CDK inhibitor dinaciclib (Dina) has been found to drastically sensitizes cancer response to TRAIL-expressing extracellular vesicle (EV-T...
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Open AccessCorrection: Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders
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Article
Associations of Multiple Serum Trace Elements with Abnormal Sleep Duration Patterns in Hospitalized Patient with Cirrhosis
The associations of circulating trace elements with sleep health have attracted increasing attention given their potential link. However, there is scant data on the relationship between serum trace elements an...
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Article
Spectrally tunable humic acid–based carbon dots: a simple platform for metronidazole and ornidazole sensing in multiple real samples
Humic acid–based carbon dots (HACDs) have excellent properties and are widely used in environmental detection, bioimaging, and optoelectronic materials. Herein, we investigated the structure–activity relations...
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Article
Molybdenum fertilizer improved antioxidant capacity of Chinese Merino sheep under compound contamination
To investigate the response of different levels of molybdenum (Mo) fertilizer to Chinese Merino sheep (Junken Type) grazing on natural heavy metal–contaminated meadows, this study was carried out in the Bayanb...
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Article
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior
Pradofloxacin is an important antibiotic with poor physical stability. At present, there is no systematic study on its polymorphic form. The purpose of this study is to develop new crystal forms to improve the...
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Article
Effects of Nano-Cu2O on the Productivity in the Cu-Stripped Chinese Merino Sheep
This research is to study the effects of nano-Cu2O on blood parameters, growth performance, and wool yield in the Cu-stripped ranches, and provide reference for further study on prevention and treatment in Cu-def...
