3 Result(s)
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Kristina Kovacovicova
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Article
Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects
Accumulation of senescent cells may drive age-associated alterations and pathologies. Senolytics are promising therapeutics that can preferentially eliminate senescent cells. Here, we performed a high-throughp...
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Article
Open AccessMild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing challenge in terms of prevention and treatment. A minority of affected patients develops inflammation, subsequently f...
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Article
The frequency of precocious segregation of sister chromatids in mouse female meiosis I is affected by genetic background
Mammalian female gametes frequently suffer from numerical chromosomal aberrations, the main cause of miscarriages and severe developmental defects. The underlying mechanisms responsible for the development of ...
