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  1. Article

    Open Access

    The spatial and temporal structure of neural activity across the fly brain

    What are the spatial and temporal scales of brainwide neuronal activity? We used swept, confocally-aligned planar excitation (SCAPE) microscopy to image all cells in a large volume of the brain of adult Drosophil...

    Evan S. Schaffer, Neeli Mishra, Matthew R. Whiteway, Wenze Li… in Nature Communications (2023)

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    Article

    High-speed light-sheet microscopy for the in-situ acquisition of volumetric histological images of living tissue

    Histological examinations typically require the excision of tissue, followed by its fixation, slicing, staining, mounting and imaging, with timeframes ranging from minutes to days. This process may remove func...

    Kripa B. Patel, Wenxuan Liang, Malte J. Casper… in Nature Biomedical Engineering (2022)

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    Article

    Real-time volumetric microscopy of in vivo dynamics and large-scale samples with SCAPE 2.0

    The limited per-pixel bandwidth of most microscopy methods requires compromises between field of view, sampling density and imaging speed. This limitation constrains studies involving complex motion or fast ce...

    Venkatakaushik Voleti, Kripa B. Patel, Wenze Li, Citlali Perez Campos… in Nature Methods (2019)