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  1. Article

    Open Access

    Optochemical control of slow-wave sleep in the nucleus accumbens of male mice by a photoactivatable allosteric modulator of adenosine A2A receptors

    Optochemistry, an emerging pharmacologic approach in which light is used to selectively activate or deactivate molecules, has the potential to alleviate symptoms, cure diseases, and improve quality of life whi...

    Koustav Roy, Xuzhao Zhou, Rintaro Otani, **-Chuan Yuan… in Nature Communications (2024)

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  2. No Access

    Article

    Hypobaric Hypoxia Induces Deficits in Adult Neurogenesis and Social Interaction via Cyclooxygenase-1/ EP1 Receptor Pathway Activating NLRP3 Inflammasome

    Low oxygen environments, like hypobaric hypoxia (HH), are common nodes in a number of diseases characterized by neuroinflammation, which is detrimental to the structural and functional aspects of hippocampal c...

    Garima Chauhan, Gaurav Kumar, Koustav Roy, Punita Kumari… in Molecular Neurobiology (2022)

  3. Article

    Open Access

    Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

    Sleep deprivation (SD) leads to cognitive impairment. Neuroinflammation could be a significant contributing factor in the same. An increase in regional brain pro-inflammatory cytokines induces cognitive defici...

    Meetu Wadhwa, Amit Prabhakar, Koushik Ray, Koustav Roy… in Journal of Neuroinflammation (2017)

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