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Chapter
Cancer Angiogenesis and Its Master Regulator Perlecan
Angiogenesis and vasculogenesis are not only indispensable for normal tissue growth and regeneration but also particularly vital for tumors. As without sufficient blood supply that provides nutrients, tumor ce...
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Chapter
The Role of Decorin in Cancer
The dynamic interactions between the tumor cells and their microenvironment consisting of stroma cells and extracellular matrix play a crucial role in cancer development. Decorin, a chondroitin sulfate/dermata...
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Chapter
The Mystery of Syndecan-1 in Tumor Development and Progression
Syndecan-1, a cell surface heparan sulfate proteoglycan, participates in a multitude of cellular processes, and it acts as a “fine tuner of cellular signaling.” Syndecan-1 is present in most epithelial tissues...