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    Chapter

    Cancer Angiogenesis and Its Master Regulator Perlecan

    Angiogenesis and vasculogenesis are not only indispensable for normal tissue growth and regeneration but also particularly vital for tumors. As without sufficient blood supply that provides nutrients, tumor ce...

    Ilona Kovalszky, Loránd Váncza in The Extracellular Matrix and the Tumor Mic… (2022)

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    Chapter

    The Role of Decorin in Cancer

    The dynamic interactions between the tumor cells and their microenvironment consisting of stroma cells and extracellular matrix play a crucial role in cancer development. Decorin, a chondroitin sulfate/dermata...

    Kornélia Baghy, Andrea Reszegi in The Extracellular Matrix and the Tumor Mic… (2022)

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    Chapter

    The Mystery of Syndecan-1 in Tumor Development and Progression

    Syndecan-1, a cell surface heparan sulfate proteoglycan, participates in a multitude of cellular processes, and it acts as a “fine tuner of cellular signaling.” Syndecan-1 is present in most epithelial tissues...

    Ilona Kovalszky, Kornélia Baghy in The Extracellular Matrix and the Tumor Mic… (2022)