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  1. Article

    Open Access

    Syndecan-1 in Liver Diseases

    Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expr...

    Eszter Regős, Katalin Karászi, Andrea Reszegi, András Kiss… in Pathology & Oncology Research (2020)

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  2. Article

    Open Access

    Inhibitory Effect of (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-amine on Lung Adenocarcinoma

    BPAP is a potent enhancer substance with catecholaminergic and serotoninergic activity in the brain. It was discovered that it is also effective against certain types of experimental cancers, showing the most ...

    Zsolt Mervai, Andrea Reszegi, Ildikó Miklya, József Knoll… in Pathology & Oncology Research (2020)

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    Article

    Chronic Hyperglycaemia Induced Alterations of Hepatic Stellate Cells Differ from the Effect of TGFB1, and Point toward Metabolic Stress

    The deleterious effect of hyperglycemia on the biology of the liver is supported by clinical evidence. It can promote the development of fatty liver, liver fibrosis, even liver cancer as complication of diabet...

    Katalin Kiss, Eszter Regős, Kristóf Rada, Gábor Firneisz… in Pathology & Oncology Research (2020)

  4. No Access

    Article

    Systematic Investigation of Expression of G2/M Transition Genes Reveals CDC25 Alteration in Nonfunctioning Pituitary Adenomas

    Dysregulation of G1/S checkpoint of cell cycle has been reported in pituitary adenomas. In addition, our previous finding showing that deregulation of Wee1 kinase by microRNAs together with other studies demon...

    Henriett Butz, Kinga Németh, Dóra Czenke, István Likó… in Pathology & Oncology Research (2017)

  5. No Access

    Article

    Response of Hepatic Stellate Cells to TGFB1 Differs from the Response of Myofibroblasts. Decorin Protects against the Action of Growth Factor

    Regardless to the exact nature of damage, hepatic stellate cells (HSCs) and other non-parenchymal liver cells transform to activated myofibroblasts, synthesizing the accumulating extracellular matrix (ECM) pro...

    Alexandra Fullár, Gábor Firneisz, Eszter Regős… in Pathology & Oncology Research (2017)

  6. No Access

    Article

    Dysregulation of microRNA Expression in Human Cervical Preneoplastic and Neoplastic Lesions

    Data discussed in recent reviews demonstrated that dysregulation of microRNA (miRNA) expression profiles occurs during cervical carcinogenesis and characteristic up- or downregulation of certain miRNAs might b...

    Ádám Galamb, Márta Benczik, Balázs Zinner, Eszter Vígh… in Pathology & Oncology Research (2015)

  7. No Access

    Article

    Treatment of Refractory Hairy Cell Leukemia with a BRAF-inhibitor: Lessons to be Learnt

    Hairy cell leukemia is a rare chronic lymphoproliferative disorder with indolent but progressive clinical course. Patients require treatment when they have significant cytopenia or recurrent infections. The go...

    Eszter Sári, Zsolt György Nagy, Kornélia Baghy… in Pathology & Oncology Research (2014)