11 Result(s)
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Koji Tamura
Science, Humanities and Social Sciences, multidisciplinary
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open Accesshoxc12/c13 as key regulators for rebooting the developmental program in Xenopus limb regeneration
During organ regeneration, after the initial responses to injury, gene expression patterns similar to those in normal development are reestablished during subsequent morphogenesis phases. This supports the ide...
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Article
Open AccessAn archetype and scaling of developmental tissue dynamics across species
Morphometric studies have revealed the existence of simple geometric relationships among various animal shapes. However, we have little knowledge of the mathematical principles behind the morphogenetic dynamic...
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Article
Open AccessDevelopmental independence of median fins from the larval fin fold revises their evolutionary origin
The median fins of modern fish that show discrete forms (dorsal, anal, and caudal fins) are derived from a continuous fold-like structure, both in ontogeny and phylogeny. The median fin fold (MFF) hypothesis a...
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Article
Open AccessRegrowth of zebrafish caudal fin regeneration is determined by the amputated length
Fish have a high ability to regenerate fins, including the caudal fin. After caudal fin amputation, original bi-lobed morphology is reconstructed during its rapid regrowth. It is still controversial whether po...
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Article
Open AccessHomeobox code model of heterodont tooth in mammals revised
Heterodonty is one of the hallmarks of mammals. It has been suggested that, homeobox genes, differentially expressed in the ectomesenchyme of the jaw primordium along the distal-proximal axis, would determine ...
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Article
Open AccessFunctional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features
Unlike microevolutionary processes, little is known about the genetic basis of macroevolutionary processes. One of these magnificent examples is the transition from non-avian dinosaurs to birds that has create...
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Article
Open AccessOpen and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization and selection
Twin-tail goldfish strains are examples of drastic morphological alterations that emerged through domestication. Although this mutation is known to be caused by deficiency of one of two duplicated chordin genes, ...
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Article
Open AccessTrunk exoskeleton in teleosts is mesodermal in origin
The vertebrate mineralized skeleton is known to have first emerged as an exoskeleton that extensively covered the fossil jawless fish. The evolutionary origin of this exoskeleton has long been attributed to th...
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Article
The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity
During embryonic development, initially similar fields can develop into distinct structures, such as the vertebrate fore- and hindlimbs. Although considerable progress has been made in our understanding of the...
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Article
Pitx2 determines left–right asymmetry of internal organs in vertebrates
The handedness of visceral organs is conserved among vertebrates and is regulated by asymmetric signals relayed by molecules such as Shh, Nodal and activin. The gene Pitx2 is expressed in the left lateral plate m...
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Article
Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud
RETINOIC acid is a putative morphogen in limb formation in the chick and other vertebrates1-5. In chick limb formation, it is thought that retinoic acid is released from the zone of polarizing activity (ZPA) and ...
