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Article
Open AccessComplete fusion of a transposon and herpesvirus created the Teratorn mobile element in medaka fish
Mobile genetic elements (e.g., transposable elements and viruses) display significant diversity with various life cycles, but how novel elements emerge remains obscure. Here, we report a giant (180-kb long) tr...
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Article
Open AccessAssociations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka species
Transcription start sites (TSSs) with pronounced and phased nucleosome arrays downstream and nucleosome-depleted regions upstream of TSSs are observed in various species.
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Article
Open AccessUnexpected link between polyketide synthase and calcium carbonate biomineralization
Calcium carbonate biominerals participate in diverse physiological functions. Despite intensive studies, little is known about how mineralization is initiated in organisms.
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Article
Open AccessTrunk exoskeleton in teleosts is mesodermal in origin
The vertebrate mineralized skeleton is known to have first emerged as an exoskeleton that extensively covered the fossil jawless fish. The evolutionary origin of this exoskeleton has long been attributed to th...
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Chapter
Double Anal Fin (Da): A Medaka Mutant Exhibiting a Mirror-Image Pattern Duplication of the Dorsal–Ventral Axis
A medaka Double anal fin (Da) mutant, spontaneously isolated from the wild-type, exhibits a unique ventralizing phenotype consisting of a mirror-image duplication across the lateral midline in the dorsal trunk-ta...
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Chapter
Chromatin-Associated Periodicity in Genetic Variation Downstream of Transcriptional Start Sites
Might DNA sequence variation reflect germline genetic activity and underlying chromatin structure? We investigated this question using the medaka (Japanese killifish, Oryzias latipes) by comparing the genomic seq...
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Article
The Tol1 transposable element of the medaka fish moves in human and mouse cells
DNA-based transposable elements can be used as tools for gene engineering and gene therapy. A great advantage over RNA-mediated elements and retroviruses is the simplicity and safety of usage. The Tol1 element of...
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Article
Open AccessThe medaka draft genome and insights into vertebrate genome evolution
The medaka fish (Oryzias latipes) is a popular pet in Japan and more recently a laboratory model organism for developmental genetics and evolutionary biology. Now the medaka's genome has been sequenced and analys...
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Article
Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka
Pigmentation of the skin is of great social, clinical and cosmetic significance. Several genes that, when mutated, give rise to altered coat color in mice have been identified; their analysis1,2,3,4,5,6 has provi...
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Article
The Medaka as a Model for Studying Germ-Cell Mutagenesis and Genomic Instability
To study germ-cell mutagenesis from the viewpoint of biodiversity, we developed a nonmammalian specific-locus test system using the Japanese medaka, Oryzias latipes. The genetic end points available are dominant...
