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Article
Neurological recovery rate and predictive factors of incomplete AIS grade C spinal cord injury in the older aged population
Retrospective cohort study.
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Article
Open AccessImpact of malnutrition on mortality and neurological recovery of older patients with spinal cord injury
This retrospective cohort study established malnutrition’s impact on mortality and neurological recovery of older patients with cervical spinal cord injury (SCI). It included patients aged ≥ 65 years with trau...
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Article
Open AccessProgression of vertebral deformity of prevalent vertebral fractures in the elderly: a population-based study
Little is known about the progression pattern of vertebral deformities in elderly patients with prevalent vertebral fractures. This population-based cohort study investigated the incidence, progression pattern...
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Article
Central sensitization as a predictive factor for the surgical outcome in patients with lumbar spinal stenosis: a multicenter prospective study
The impact of central sensitization (CS) on neurological symptoms and surgical outcomes in patients with lumbar spinal stenosis (LSS) remains unknown. This study aimed to investigate the influence of preoperat...
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Article
Open AccessRegenerative effects of platelet-rich plasma releasate injection in rabbit discs degenerated by intradiscal injection of condoliase
Intradiscal condoliase injection is an alternative therapeutic option for lumbar disc herniation (LDH). However, it is often associated with disc degeneration. Several in vivo studies have demonstrated the reg...
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Article
Prognostic impact of respiratory dysfunction in elderly patients with cervical spinal cord injury and/or fractures: a multicenter survey
To investigate the impact of early post-injury respiratory dysfunction for neurological and ambulatory ability recovery in patients with cervical spinal cord injury (SCI) and/or fractures.
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Open AccessCharacteristics of the cervical spine and cervical cord injuries in older adults with cervical ossification of the posterior longitudinal ligament
Although the incidence of cervical spinal cord injury (CSCI) with ossification of the posterior longitudinal ligament (OPLL) has increased in older adults, its etiology and neurological outcomes remain unknown...
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Article
Change in prevalence of vertebral fractures over two decades: a Japanese medical examination-based study
Although remarkable progress has been made in osteoporosis treatment over the last two decades, no study has reported the change in the prevalence of vertebral fractures (VFs) during this time. This study aime...
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Article
Open AccessDifferences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases
Although traumatic cervical spine injuries in older adults are commonly caused by minor traumas, such as ground-level falls, their prognosis is often unfavorable. Studies examining the clinical characteristics...
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Article
Open AccessA multicenter study of 1-year mortality and walking capacity after spinal fusion surgery for cervical fracture in elderly patients
The 1-year mortality and functional prognoses of patients who received surgery for cervical trauma in the elderly remains unclear. The aim of this study is to investigate the rates of, and factors associated w...
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Article
Open AccessIntradiscal injection of monosodium iodoacetate induces intervertebral disc degeneration in an experimental rabbit model
Establishing an optimal animal model for intervertebral disc (IVD) degeneration is essential for develo** new IVD therapies. The intra-articular injection of monosodium iodoacetate (MIA), which is commonly u...
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Article
Three-dimensional computed tomographic evaluation of lateral lumbar interbody fusion: morphometric change of intervertebral structure
Two-dimensional (2D) analyses of intervertebral disc (IVD) height and foramen measurements following lateral lumbar interbody fusion (LLIF) have been reported. However, three-dimensional (3D) morphometric anal...
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Article
Open AccessAssociation between non-traumatic vertebral fractures and adjacent discs degeneration: a cross-sectional study and literature review
Previous clinical studies reported that thoracolumbar vertebral fractures (VFs) associated with high energy spine trauma cause adjacent intervertebral disc (IVD) degeneration; however, the effect of non-trauma...
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Article
Open AccessCervical schwannoma in the early stage of pregnancy: a case report
Although spinal schwannomas generally grow very slowly, it has been reported that these clinical growths and their associated neurological symptoms accelerate during pregnancy. Because these cases are rare, su...
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Article
Open AccessEffect of diminished flow in rabbit lumbar arteries on intervertebral disc matrix changes using MRI T2-map** and histology
Impaired lumbar artery flow has been reported in clinical and epidemiological studies to be associated with low back pain and lumbar disc degeneration. However, it has not been experimentally demonstrated that...
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Article
Open AccessEndplate and intervertebral disc injuries in acute and single level osteoporotic vertebral fractures: is there any association with the process of bone healing?
The endplate-intervertebral disc (IVD) complex is closely interrelated with the vertebral body (VB) in the structural integrity of the anterior spinal column, including biomechanical and biological functions. ...
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Article
Open AccessExpression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
The expression of the receptor activator of nuclear factor kappa B (RANK) /RANK ligand (RANKL) /osteoprotegerin (OPG) system and its association with the progression of intervertebral disc (IVD) degeneration h...
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Article
Open AccessMorphology of intervertebral disc ruptures evaluated by vacuum phenomenon using multi-detector computed tomography: association with lumbar disc degeneration and canal stenosis
The progression of intervertebral disc (IVD) degeneration leads to rupture within IVD tissues. The location and appearance of areas of gaseous radiolucency in the IVD, known as vacuum phenomena (VPs), are cons...
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Article
Open AccessRANK/RANKL/OPG system in the intervertebral disc
The receptor activator of NF-κB ligand (RANKL), a member of the TNF ligand superfamily, is known to regulate bone metabolism. The expression of each component of the RANK/RANKL/osteoprotegerin (OPG) system in ...
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Article
Open AccessAtlantoaxial rotatory fixation as a rare complication from head positioning in otologic surgery: Report of two cases in young children
Atlantoaxial rotatory fixation is a condition in which the first and second vertebrae of the cervical spine become interlocked in a rotated position. This condition can result in serious consequences and thus ...