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Open AccessNew molecular staging with G-factor supplements TNM classification in gastric cancer: a multicenter collaborative research by the Japan Society for Gastroenterological Carcinogenesis G-Project committee
The G-Project committee was erected by the Japan Society for Gastroenterological Carcinogenesis with an aim of establishing a new classification scheme based on molecular biological characteristics that would ...
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A hepatocellular neoplasm accompanied with massive histiocyte infiltration
This report presents the case of a unique hepatocellular nodule occurring in a 73-year-old Japanese male with diabetes mellitus and mild obesity. The nodule consisted of hepatocyte-like tumor cells and abundan...
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Fibroadenoma of the gallbladder with borderline malignancy: a poorly recognized gallbladder tumor
Fibroadenoma of the gallbladder is extremely rare tumor, with only two cases reported in the world. It is characterized by abundant loose edematous connective tissue, glandular structure, polypoid structure co...
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A long-time survivor of alpha-fetoprotein-producing gastric cancer successfully treated by fluoropyrimidine-based chemotherapy: a case study
A 67-year-old male with advanced gastric cancer and lymph node metastasis as well as a tumor embolus in the portal vein was treated by S-1/cisplatin therapy. The serum alpha-fetoprotein levels were elevated to...
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Bleeding and stenosis caused by reflux esophagitis was not common in emergency endoscopic examinations: a retrospective patient chart review at a single institution in Japan
Bleeding and stenosis are serious complications of reflux esophagitis, although few studies have been performed in Japan regarding these complications. This study aimed to indicate the characteristics of reflu...
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Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients
Aberrant methylation of some cancer-related genes has been reported to correlate with sensitivity to chemotherapeutic agents. The present study was designed to determine whether DNA methylation in six cancer-r...
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Endoscopic hemostasis for bleeding gastric varices treated by combination of variceal ligation and sclerotherapy with N-butyl-2-cyanoacrylate
Bleeding from esophagogastric varices is a serious complication of portal hypertension. The aim of the present study was to determine whether endoscopic sclerotherapy with injection of N-butyl-2-cyanoacrylate com...
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Aberrant promoter hypermethylation in biliary tract carcinoma
Biliary tract carcinoma is a relatively rare tumor with a poor survival rate. The molecular biological mechanisms underlying the development of biliary tract carcinomas are not well understood. Promoter methyl...
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Gastrointestinal function and quality of life after pylorus-preserving pancreatoduodenectomy
The pylorus-preserving pancreatoduodenectomy (PPPD) has taken the place of the conventional Whipple pancreato-duodenectomy as the standard procedure for various periampullary disease. With recent advances in s...
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The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer
We studied the correlations between CHFR (checkpoint with FHA and RING finger) gene methylation and responses to microtubule inhibitors (MI) in gastric cancer.
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Loss of expression of DNA repair enzymes MGMT, hMLH1, and hMSH2 during tumor progression in gastric cancer
Disorders of the DNA repair system that protects against alkylating mutagens are known to play an important role in carcinogenesis.
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Benign nonepithelial fibroma in the pancreas
This is, to our knowledge, the first report of a fibroma originating in the pancreas in which preoperative imaging findings or explicit descriptions of histopathologic observations are clearly described. A 64...
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Focal pancreatic hemorrhage mimicking pancreas carcinoma with lymph node metastasis
A 67-year-old man was referred to our department because of a mass in the pancreas tail. Pancreatic tail cancer with lymph node metastasis was diagnosed, based on various radiological findings. Computed tomog...
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Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings
Two distinct epithelial lesions (dysplasia and adenoma) and one high-risk condition (anomalous pancreatico-biliary ductal junction; APBDJ) are currently recognized as premalignant stages of gallbladder carcin...
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Establishment and characterization of human hilar bile duct carcinoma cell line and cell strain
We established and characterized a human hilar bile duct carcinoma (HBDC) cell line from cells isolated from the ascites of a 75-year-old Japanese woman. Histopathological findings were confirmed to be poorly...
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Polypoid adenomyoma of the gallbladder
We describe a distinctive polypoid lesion of the gallbladder (16 mm in diameter) at the fundus, associated with a granulomatous mass in the liver adjacent to the gallbladder fossa, in a 64-year-old Japanese wo...
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Benign gallbladder lesions mimicking cancer infiltrating the liver
Considering the current improved resectability of advanced gallbladder cancers, differentiation from benign gallbladder lesions mimicking advanced cancer is now a significant problem to be overcome so that unn...
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5th Japanese Association of Hepato-Biliary-Pancreatic Surgery
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Abstracts of Selected Papers Presented at the 76th General Meeting of the Japanese Society of Gastroenterology