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  1. Article

    Open Access

    Culture-space control is effective in promoting haploid cell formation and spermiogenesis in vitro in neonatal mice

    The classical organ culture method, in which tissue is placed at the gas‒liquid interphase, is effective at inducing mouse spermatogenesis. However, due to reginal variations in the supply of oxygen and nutrie...

    Kiyoshi Hashimoto, Hisakazu Odaka, Yu Ishikawa-Yamauchi, Shino Nagata in Scientific Reports (2023)

  2. Article

    Open Access

    Generation of rat offspring using spermatids produced through in vitro spermatogenesis

    An in vitro spermatogenesis method using mouse testicular tissue to produce fertile sperm was established more than a decade ago. Although this culture method has generally not been effective in other animal s...

    Takafumi Matsumura, Kumiko Katagiri, Tatsuma Yao in Scientific Reports (2023)