1 Result(s)

Article

Tadalafil increases the antitumor activity of 5-FU through inhibiting PRMT5-mediated glycolysis and cell proliferation in colorectal cancer

Protein arginine methyltransferase 5 (PRMT5) is upregulated in multiple tumors and plays a pivotal role in cancer cell proliferation. However, the role of PRMT5 in colorectal cancer remains poorly understood.

Yao Shen, Pan Zhao, Kewei Dong, Jiajia Wang, Huichen Li, Mengyang Li… in Cancer & Metabolism (2022)