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  1. No Access

    Article

    Development and testing of a surface roughness measurement device based on aerial ultrasonic reflections

    Repairs of concrete irrigation channels in Japan are guided to a large extent by the degree to which their walls have degraded over decades of use. Current methods of estimating Manning roughness coefficients ...

    Kenji Okajima, Seiya Nagaoka, Mohammad Raihanul Islam… in Paddy and Water Environment (2020)

  2. No Access

    Article

    Development of a measurement method for abrasion irrigation channel using underwater ultrasonic wave

    Japan has many concrete irrigation channels with total length of about 400,000 km. Most of these channels are now too old for continued use. It would be too costly to reconstruct these channels. The concrete s...

    Seiya Nagaoka, Kenji Okajima, Ryoei Ito, Ken Watanabe… in Paddy and Water Environment (2019)

  3. No Access

    Article

    The tendency of damage of stone walls in terrace fields in the northwestern Kumamoto City by the 2016 Kumamoto Earthquake and heavy rain in 2016 and 2006

    The topographical features of farmland stone walls that were damaged by two heavy rains and the 2016 Kumamoto Earthquake were studied. Topographical analyses were performed on data for sites of the damaged far...

    Kenji Okajima, Shoko Nishiwaki in Paddy and Water Environment (2019)

  4. No Access

    Chapter

    New Aspects of Antiinflammatory Activity of Antithrombin: Molecular Mechanism(s) and Therapeutic Implications

    Antithrombin (AT), an important natural anticoagulant, has been shown to reduce various organ failures as well as coagulation abnormalities in animal sepsis models and in patients with severe sepsis. Proinflam...

    Naoaki Harada, Kenji Okajima in Recent Advances in Thrombosis and Hemostasis 2008 (2008)

  5. No Access

    Article

    Inhibition of Neutrophil Activation by Lafutidine, an H2-receptor Antagonist, Through Enhancement of Sensory Neuron Activation Contributes to the Reduction of Stress-Induced Gastric Mucosal Injury in Rats

    Sensory neuron activation reduces water-immersion restraint stress (WIR)-induced gastric mucosal injury by inhibiting neutrophil activation through increase in endothelial production of prostacyclin. This stud...

    Naoaki Harada, Kenji Okajima in Digestive Diseases and Sciences (2007)

  6. No Access

    Chapter

    Neuroinflammation as an Important Pathogenic Mechanism in Spinal Cord Injury

    Acute traumatic spinal cord injury (SCI) is an unexpected, catastrophic event, the consequences of which often persist for the life of the patient and influence in diverse ways not only the patient but also fa...

    Yuji Taoka, Kenji Okajima in Neuroinflammation (2003)

  7. No Access

    Article

    A Comparative Double-Blind Randomized Trial of Activated Protein C and Unfractionated Heparin in the Treatment of Disseminated Intravascular Coagulation

    A randomized prospective double-blind trial was performed to compare the safety and efficacy of human activated protein C (APC) and unfractionated heparin for the treatment of disseminated intravascular coagul...

    Nobuo Aoki, Tamotsu Matsuda, Hidehiko Saito… in International Journal of Hematology (2002)

  8. No Access

    Article

    Activated Neutrophils Impair Gastric Cytoprotection: Role of Neutrophil Elastase

    Neutrophil elastase decreases production of PGI2 by cultured endothelial cells. Thus, neutrophil elastase may play an important role in gastric mucosal injury by decreasing the tissue level of PGI2, an important ...

    Naoaki Harada, Kenji Okajima, Wenge Liu… in Digestive Diseases and Sciences (2000)

  9. No Access

    Article

    The Role of Leukocytes in Disseminated Intravascular Coagulation Associated with Sepsis

    Leukocytes play a pivotal role in the pathogenesis of disseminated intravascular coagulation (DIC) and multiple organ failure associated with sepsis. Cytokines such as tumor necrosis factor-a (TNF-α) and inter...

    Kenji Okajima in Sepsis (1999)

  10. No Access

    Article

    Rebamipide Attenuates Indomethacin-Induced Gastric Mucosal Lesion Formation by Inhibiting Activation of Leukocytes in Rats

    Granulocyte elastase released from activatedleukocytes plays an important role in leukocyteinfiltration. Since activated leukocytes have been shownto be involved in the pathogenesis of gastric mucosal lesion f...

    Kazunori Murakami, Kenji Okajima, Mitsuhiro Uchiba… in Digestive Diseases and Sciences (1997)

  11. No Access

    Chapter

    Gastric Prostacyclin (PGI2) Prevents Stress-Induced Gastric Mucosal Injury in Rats by Inhibiting Leukocyte Activation

    Prostaglandins play an important role in preventing gastric mucosal injury, referred to as “gastric cytoprotection”. Although PGE1 and PGE2 inhibit gastric secretion, cytoprotection is considered independent of t...

    Naoaki Harada, Kenji Okajima… in Recent Advances in Prostaglandin, Thrombox… (1997)

  12. No Access

    Article

    Protective Effects of Antithrombin III Supplementation on Warm Ischemia and Reperfusion Injury in Rat Liver

    p < 0.01), and the recovery of tissue blood flow markedly improved ( p < 0.01) compared to the saline-treated group (control group). Leakages of ...

    Keiichi Okano, Yasutaka Kokudo, Kenji Okajima… in World Journal of Surgery (1996)