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within Kemal Keseroglu Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    Stochastic gene expression and environmental stressors trigger variable somite segmentation phenotypes

    Mutations of several genes cause incomplete penetrance and variable expressivity of phenotypes, which are usually attributed to modifier genes or gene-environment interactions. Here, we show stochastic gene ex...

    Kemal Keseroglu, Oriana Q. H. Zinani, Sevdenur Keskin… in Nature Communications (2023)

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  2. No Access

    Article

    Pairing of segmentation clock genes drives robust pattern formation

    Gene expression is an inherently stochastic process1,2; however, organismal development and homeostasis require cells to coordinate the spatiotemporal expression of large sets of genes. In metazoans, pairs of co-...

    Oriana Q. H. Zinani, Kemal Keseroğlu, Ahmet Ay, Ertuğrul M. Özbudak in Nature (2021)