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Article
A Novel Alzheimer-Associated SNP in Tmp21 Increases Amyloidogenesis
Recent studies suggest that TMP21 is a selective modulator of γ-secretase and its dysregulation affects APP processing, leading to increased Aβ generation. However, the genetic association between Tmp21 and Alzhe...
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Article
Open AccessTranscriptional Regulation of TMP21 by NFAT
TMP21 is a member of the p24 cargo protein family, which is involved in protein transport between the Golgi apparatus and ER. Alzheimer's Disease (AD) is the most common neurodegenerative disorder leading to d...