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  1. No Access

    Article

    Lipopolysaccharide-Educated Cancer-Associated Fibroblasts Facilitate Malignant Progression of Ovarian Cancer Cells via the NF-kB/IL-6/JAK2 Signal Transduction

    Gram-negative bacteria increase in ovarian cancer (OC) tissues, but its association with OC progression remains largely unknown. The present study aimed to investigate whether and how cancer-associated fibrobl...

    Dongjie Wang, Lingchuan Li, Yifeng Zhang, Kefan Ye in Molecular Biotechnology (2024)

  2. No Access

    Article

    Upregulation of HTRA1 mediated by the lncRNA NEAT1/miR-141-3p axis contributes to endometriosis development through activating NLRP3 inflammasome-mediated pyroptotic cell death and cellular inflammation

    The present study identified a novel upstream long chain non-coding (lncRNA) NEAT1/miR-141-3p/HTRA1 axis that regulated the activation of NLR family pyrin domain containing 3 (NLRP3) inflammasome to modulate e...

    Lingchuan Li, Kefan Ye, Dongjie Wang in In Vitro Cellular & Developmental Biology - Animal (2023)

  3. No Access

    Article

    METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A/VEGF pathway

    Gestational choriocarcinoma is a highly malignant neoplastic disease derived from pathological changes in trophoblastic cells. Recent evidences have shown that N6-methyladenosine (m6A) modifications play impor...

    Kefan Ye, Lingchuan Li, Bao Wu, Dongjie Wang in Genes & Genomics (2022)