10 Result(s)

Article

Condensation matters

Membrane-less organelles formed by liquid–liquid phase separation provide additional cellular compartmentalization for precise spatiotemporal regulation of biological processes. Ke Ruan, Yi Lin, Peiguo Yang an...

Ke Ruan, Yi Lin, Peiguo Yang, Wen Zhou in Nature Chemical Biology (2023)

Article

Enhanced edge convolution-based spatial-temporal network for network traffic prediction

Accurately predicting network traffic is helpful for improving a variety of spatial-temporal data mining applications, such as intelligent traffic control, network planning and anomaly detection. The mainstrea...

Zehua Hu, Ke Ruan, Weihao Yu, Siyuan Chen in Applied Intelligence (2023)

Article

Routing hypergraph convolutional recurrent network for network traffic prediction

Effectively predicting network traffic is a fundamental but intractable task in IP network management and operations. Many methods that can capture complex spatiotemporal dependencies from network topology and...

Weihao Yu, Ke Ruan, Hong Tang, ** Huang in Applied Intelligence (2023)

Article

Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets

Liang Wang, Wen-Tao Hou, Jie Wang, Da Xu, Cong Guo, Linfeng Sun, Ke Ruan… in Cell Research (2022)

Article

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

Spindle position control is essential for cell fate determination and organogenesis. Early studies indicate the essential role of the evolutionarily conserved Gαi/LGN/NuMA network in spindle positioning. Howev...

**aoyu Song, Fengrui Yang, Xu Liu, Peng **a, Wu Yin, Zhikai Wang… in Nature Chemical Biology (2021)

Article

k-dominant Skyline query algorithm for dynamic datasets

At present, most k-dominant Skyline query algorithms are oriented to static datasets, this paper proposes a k-dominant Skyline query algorithm for dynamic datasets. The algorithm is recursive circularly. First, w...

Zhiyun Zheng, Ke Ruan, Mengyao Yu, **ng** Zhang… in Frontiers of Computer Science (2020)

Article

BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules

Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit....

Yuejia Huang, Lin Lin, **ng Liu, Sheng Ye, Phil Y. Yao, Wenwen Wang… in Cell Research (2019)

Article

Allosteric mechanisms underlie GPCR signaling to SH3-domain proteins through arrestin

Signals from 800 G-protein-coupled receptors (GPCRs) to many SH3 domain-containing proteins (SH3-CPs) regulate important physiological functions. These GPCRs may share a common pathway by signaling to SH3-CPs ...

Fan Yang, Peng **ao, Chang-xiu Qu, Qi Liu, Liu-yang Wang… in Nature Chemical Biology (2018)

Article

De novo determination of internuclear vector orientations from residual dipolar couplings measured in three independent alignment media

The straightforward interpretation of solution state residual dipolar couplings (RDCs) in terms of internuclear vector orientations generally requires prior knowledge of the alignment tensor, which in turn is ...

Ke Ruan, Kathryn B. Briggman, Joel R. Tolman in Journal of Biomolecular NMR (2008)