35 Result(s)
within
Ke Jian Liu
English
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Chapter
Measurements of pO2 in Vivo, Including Human Subjects, by Electron Paramagnetic Resonance
The purpose of this paper is to provide an illustrative description of the current state of development of the use of electron paramagnetic resonance (EPR, or completely equivalently, electron spin resonance o...
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Chapter
Thermo-Induced Phase Transitions and Regulation of Permeability of Biomimetic Membranes
For many years membrane science was essentially subdivided into two major fields: artificial membranes used mainly in separation/purification technology and biological membranes. During the last ten years howe...
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Article
An HPLC and EPR investigation on the stability of DMPO and DMPO spin adducts in vivo
Application of the spin trap** technique in intact animals requires an understanding of the stability and distribution of the spin traps and their spin adducts in vivo. We studied the stability of DMPO in vivo ...
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Article
Low frequency epr surface probe based on dielectric resonator
A new surface probe for low frequency in vivo EPR studies was designed and constructed based on a dielectric resonator. Dielectric resonators previously have been used in X-band EPR for small samples to take adva...
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Chapter
Effect of Anesthesia on Cerebral Tissue Oxygen and Cardiopulmonary Parameters in Rats
General anesthesia is known to alter cardiopulmonary and hematological parameters which affect tissue oxygenation. However, the effect of various types of anesthetics on the relationship between brain tissue pO2 ...
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Chapter
Comparisons of Measurements of pO2 in Tissue In Vivo by EPR Oximetry and Micro-Electrodes
Polarographic micro-electrode measurements are very useful for measuring pO2 in vivo, especially for measurements of the variation of pO2 within a tumor (1,2,8). This method has se...
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Chapter
Effects of Ketamine/Xylazine and Pentobarbital Anesthesia on Cerebral Tissue Oxygen Tension, Blood Pressure, and Arterial Blood Gas in Rats
General anesthesia is needed in many animal experiments in order to carry the studies out in an effective and appropriate manner. The concentration of oxygen in tissues is often a critical variable in many of ...
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Chapter
In vivo reduction of chromium (VI) and its related free radical generation
Chromium (VI) compounds are widely recognized as human carcinogens. Extensive studiesin vitroand in model systems indicate that the reactive intermediate, Cr (V), generated by cellular reduction of Cr (VI), is li...
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Article
On the application of 4-hydroxybenzoic acid as a trap** agent to study hydroxyl radical generation during cerebral ischemia and reperfusion
Aromatic hydroxylation from the reaction between hydroxyl radical and salicylate or its related compounds has been often utilized as a marker for the generation of hydroxyl radicals. We have investigated sever...
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Chapter
Spin Trap** in Vivo: Facts and Artifacts
EPR spectroscopy is a powerful technique for the detection, identification and quantification of free radical species, and, as can be seen from other chapters in this work, has been widely used both to study b...
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Article
Oxidative mechanism of arsenic toxicity and carcinogenesis
Arsenic is a known toxin and carcinogen that is present in industrial settings and in the environment. The mechanisms of disease initiation and progression are not fully understood. In the last a few years, th...
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Chapter and Conference Paper
On the Stochastic Overlay Simulation Network
This paper proposes a method of generating stochastic overlay simulation network with exact average degree (EAD). It discusses regional distribution of stochastic nodes, selection of core nodes and overlay fun...
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Article
Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes
Arsenic is a naturally occurring element that is present in food, soil, and water. Inorganic arsenic can accumulate in human skin and is associated with increased risk of skin cancer. Oxidative stress due to a...
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Article
Arseniasis prevalence and mortality in a multiethnic, endemic township in Guizhou, China
Farmers in Southwest Guizhou Autonomous Prefecture, China, represent a unique case of arseniasis, which is related to indoor combustion of high arsenic-containing coal instead of to arsenic-contaminated drinki...
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Article
Effect of fluoride exposure on bone metabolism indicators ALP, BALP, and BGP
To analyze the changes in serum alkaline phosphatase (ALP) and bone alkaline phosphatase (BALP) activity and changes in osteocalcin (BGP) content following fluoride exposure and, thereby, determine the referen...
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Article
Open AccessNormobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke
Normobaric hyperoxia (NBO) has been shown to be neuro- and vaso-protective during ischemic stroke. However, the underlying mechanisms remain to be fully elucidated. Activation of NADPH oxidase critically contr...
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Article
The Influence of Fluoride on the Expression of Inhibitors of Wnt/β-Catenin Signaling Pathway in Rat Skin Fibroblast Cells
The effective therapy of fluoride-induced bone diseases requires an understanding of the mechanism of the disorders. Changes in the inhibitors of the Wnt/β-catenin pathway, Dickkopf-1 (Dkk-1) and Sclerostin (S...
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Article
Open AccessNormobaric hyperoxia-based neuroprotective therapies in ischemic stroke
Stroke is a leading cause of death and disability due to disturbance of blood supply to the brain. As brain is highly sensitive to hypoxia, insufficient oxygen supply is a critical event contributing to ischem...
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Article
AKT-Related Autophagy Contributes to the Neuroprotective Efficacy of Hydroxysafflor Yellow A against Ischemic Stroke in Rats
Hydroxysafflor yellow A (HSYA) has been approved clinically for treating cardiac patients in China since 2005. Recent studies have indicated that HSYA may be neuroprotective at 24 h in experimental stroke mode...
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Article
Open AccessExtended normobaric hyperoxia therapy yields greater neuroprotection for focal transient ischemia-reperfusion in rats
Normobaric hyperoxia (NBO) therapy is neuroprotective in acute ischemic stroke. However, how long the NBO should last to obtain optimal outcome is still unclear. Reports show that ischemic penumbra blood suppl...
