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  1. No Access

    Article

    Opportunities for Neuroprotective Drugs in the Era of Vascular Recanalization

    Zhifeng Qi, Ke Jian Liu in Translational Stroke Research (2024)

  2. No Access

    Article

    Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway

    Tissue plasminogen activator (t-PA) has a restrictive therapeutic window within 4.5 h after ischemic stroke with the risk of hemorrhagic transformation (HT) and neurotoxicity when it is used beyond the time wi...

    Hansen Chen, Binghe Guan, ** Chen, **ngmiao Chen… in Translational Stroke Research (2018)

  3. No Access

    Article

    Normobaric Hyperoxia Extends Neuro- and Vaso-Protection of N-Acetylcysteine in Transient Focal Ischemia

    N-acetylcysteine (NAC), a precursor of glutathione that reduces reperfusion-induced injury, has been shown protection when it was administered pre-ischemia. However, less is known about t...

    Yushan Liu, Wen-Cao Liu, Yanyun Sun, **anzhi Shen, **aona Wang… in Molecular Neurobiology (2017)

  4. No Access

    Article

    Bcl-2 Phosphorylation Triggers Autophagy Switch and Reduces Mitochondrial Damage in Limb Remote Ischemic Conditioned Rats After Ischemic Stroke

    Autophagy, an important intracellular degradation pathway, has been reported to clear impaired mitochondria and reduce mitochondria-mediated injury in ischemic disease. Our study and other recent investigation...

    Zhifeng Qi, Wen Dong, Wenjuan Shi, Rongliang Wang… in Translational Stroke Research (2015)

  5. No Access

    Article

    AKT-Related Autophagy Contributes to the Neuroprotective Efficacy of Hydroxysafflor Yellow A against Ischemic Stroke in Rats

    Hydroxysafflor yellow A (HSYA) has been approved clinically for treating cardiac patients in China since 2005. Recent studies have indicated that HSYA may be neuroprotective at 24 h in experimental stroke mode...

    Zhifeng Qi, Feng Yan, Wenjuan Shi, Chencheng Zhang… in Translational Stroke Research (2014)