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Article
Abnormal Rhythms Associated with Persistent Left Superior Vena Cava
Extract: The electrocardiograms of 26 patients with persistent left superior vena cava (SVC) draining into the coronary sinus were reviewed. Left axis of P waves between +15 and −29 degrees was observed in nin...
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Article
Dilatation of the Ductus Arteriosus by Prostaglandins and Prostaglandin's Precursors
Summary: We studied the effects of prostaglandins and their precursors in animal models. Rabbit ductus arteriosus constricted rapidly after delivery. PGE1, PDE2, and arachidonic acid injected SC dilated the ductu...
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Article
Constriction of the Fetal Ductus Arteriosus by Glucocorticoid Hormones
Summary: Hydrocortisone, prednisolone, and betamethasone were injected into a rat that was 21 days pregnant, and the fetal ductus arteriosus was studied using the rapid whole-body freezing technique. All these...
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Article
Characteristic Morphology of the Constricted Fetal Ductus Arteriosus following Maternal Administration of Indomethacin
ABSTRACT: Indomethacin 10 mg/kg was administered to the maternal rat on the 21st day of pregnancy, and the fetal and neonatal ductus arteriosus were studied using the rapid whole-body freezing technique. The s...
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Chapter
Natural history and noninvasive of diagnosis of subpulmonic ventricular septal defect
Studies made on surgical as well as on autopsy cases of ventricular septal defect (VSD) at our Institute have indicated that after the (peri)membranous type of VSD, subpulmonic VSD (SPVSD; subarterial infundib...
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Chapter and Conference Paper
Cardiovascular Malformations in the Conotruncal Anomaly Face Syndrome
In 1976, we reported a peculiar facial appearance [1] specifically related to conotruncal anomalies of the heart that was thus named “conotruncal anomaly face” (CTAF) and was characterized by lateral displacem...
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Chapter and Conference Paper
Characteristic Constriction of the Fetal Ductus Arteriosus by Indomethacin Administered to the Mother Rat
The study of Sharpe et al. has shown that the fetal ductus arteriosus (DA) constricts following administration of indomethacin and sodium salicylate to pregnant rats [1]. Further studies on pharmacologic manip...
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Article
Detection of the drainage site in anomalous pulmonary venous connection by two-dimensional Doppler color flow-map** echocardiography
Ten patients with total and one with partial anomalous pulmonary venous connection were studied by two-dimensional Doppler color flow-map** echocardiography. In cases of anomalous pulmonary venous drainage i...
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Article
Hypertrophy and diminished cavity of the right ventricle following ductal constriction in fetal rats
A morphological study using the rapid whole-body freezing technique revealed in utero development of hypertrophy and diminished cavity of the right ventricle caused by fetal ductal constriction.
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Article
An infant with dilated cardiomyopathy confirmed as myocarditis by endomyocardial biopsy
A case of an 11-month-old infant who was incidentally diagnosed as having myocarditis by right and left ventricular endomyocardial biopsy is reported. This patient was admitted because of heart failure. Chest ...
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Article
In Situ Morphology of the Heart and Great Vessels in Fetal and Newborn Rats
ABSTRACT. Morphology of the cardiac chambers and great vessels of fetal and neonatal rats was studied using the whole body freezing technique and by sectioning through the short axis of the heart with a freezi...
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Article
In Vivo Constriction of the Ductus Arteriosus by Nonsteroidal Antiinflammatory Drugs in Near-Term and Preterm Fetal Rats
ABSTRACT. Herein we report age differences of in vivo constriction of the fetal ductus arteriosus by nonsteroidal antiinflammatory drugs in near-term and preterm rats. Two potent nonsteroidal antiinflammatory dru...
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Article
Increased Constriction of the Ductus Arteriosus with Combined Administration of Indomethacin and Betamethasone in Fetal Rats
ABSTRACT: To find a better treatment for patent ductus arteriosus of preterm infants, we studied the combined effect of indomethacin and betamethasone on the fetal ductus in rats. We used a rapid whole-body fr...
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Article
Fetal Cardiovascular Effects of Nifedipine in Rats
ABSTRACT: In this study we clarify the fetal cardiovascular effects of nifedipine. Nifedipine was administered to near-term rats and cardiovascular morphology of the fetus was studied with a rapid whole-body f...
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Article
Abnormal development of fourth aortic arch derivatives in the pathogenesis of tetralogy of Fallot
Aortic arch (AoA) anomalies were studied in 233 patients with tetralogy of Fallot (TOF) of whom some had coexisting pulmonary atresia (PA). There was a 23% incidence of a right AoA in patients without PA, 21% ...
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Article
Ostial stenosis of the left coronary artery as a sole clinical manifestation of Takayasu's arteritis: A possible cause of unexpected sudden death
An 11-year-old girl experienced several syncopal attacks and her electrocardiogram showed ST depression with exercise. Ostial stenosis of the left coronary artery was disclosed by the coronary angiography. We ...
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Article
Imperforate tricuspid valve with dysplasia of the right ventricular myocardium, pulmonary valve, and coronary artery: A clinicopathological study of nine cases
Nine cases of imperforate tricuspid valve associated with dysplasia of the right ventricular myocardium, pulmonary valve, and right coronary artery are described. The mean frontal QRS axis of the electrocardio...
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Article
Color Doppler and transesophageal echocardiography of vascular sling
Three patients with vascular sling were studied by two-dimensional and color Doppler echocardiography and angiocardiography. One case was associated with atrial septal defect and another with tetralogy of Fall...
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Article
In Situ Morphology of the Ductus Venosus and Related Vessels in the Fetal and Neonatal Rat
ABSTRACT: In situ cross-sectional morphology of the ductus venosus and related vessels was studied after rapid whole-body freezing of the fetal and neonatal rat. In the fetus, the ductus venosus was open widely, ...
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Article
In Situ Morphology of the Foramen Ovale in the Fetal and Neonatal Rat
ABSTRACT: In situ cross-sectional morphology of the foramen ovale was studied after rapid whole-body freezing of the fetal and neonatal rat. In the fetus, the foramen ovale was open widely toward the left atrium ...