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Article

Graft protective effects and donor-specific antibody suppression by CD4⁺CD25⁺Foxp3⁺ regulatory T cell induced by HMG-CoA reductase inhibitor rosuvastatin in a murine heart transplant model

We previously demonstrated that the hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor (statins) play an important role in the regulation of alloimmune responses. However, little is known regarding the ef...

Kazuhito Iguchi, Yasuto Yamamoto, Masateru Uchiyama… in Journal of Cardiothoracic Surgery (2024)