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  1. No Access

    Article

    Severity of constipation related to palonosetron during first-line chemotherapy: a retrospective observational study

    Palonosetron, a long-acting 5-HT3 receptor antagonist, is an effective antiemetic agent for chemotherapy-induced nausea and vomiting; however, it sometimes causes severe constipation. The aim of the present study...

    Sakiko Kimura, Kazuhisa Hosoya, Kenji Ogata, Tatsuya Furuno… in Supportive Care in Cancer (2021)

  2. Article

    Open Access

    Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients

    KRAS mutations have been recognized as predictive markers of primary resistance to anti-EGFR-antibodies in colorectal cancer patients. In addition, newly detected KRAS mutations have been...

    Kazuhisa Hosoya, Satoshi Matsusaka, Tomomi Kashiwada… in Pathology & Oncology Research (2017)

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  3. No Access

    Article

    Failure mode and effects analysis of medication adherence in patients with chronic myeloid leukemia

    Poor adherence to ABL tyrosine kinase inhibitors (ABL TKIs) is associated with reduced treatment efficacy and increased healthcare costs. To examine the hazards associated with poor adherence, we implemented f...

    Kazuhisa Hosoya, Sakiko Mochinaga… in International Journal of Clinical Oncology (2015)