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  1. No Access

    Article

    Automated machine learning approach for develo** a quantitative structure–activity relationship model for cardiac steroid inhibition of Na+/K+-ATPase

    Quantitative structure–activity relationship (QSAR) modeling is a method of characterizing the relationship between chemical structures and biological activity. Automated machine learning enables computers to ...

    Yohei Takada, Kazuhiro Kaneko in Pharmacological Reports (2023)

  2. No Access

    Article

    Interaction of Odoroside A, A Known Natural Cardiac Glycoside, with Na+/K+-ATPase

    The nature of odoroside A, a cardiac glycoside (CG) extracted from Nerium oleander, as well as its chemical structure is quite similar to a well-known CG, ouabain possessing a steroid skeleton, a five-membered un...

    Yohei Takada, Kazuhiro Kaneko, Yoshiyuki Kawakami in The Journal of Membrane Biology (2023)

  3. Article

    A non-randomized confirmatory trial of an expanded indication for endoscopic submucosal dissection for intestinal-type gastric cancer (cT1a): the Japan Clinical Oncology Group study (JCOG0607)

    Endoscopic resection has been limited to intestinal-type gastric cancer (cT1a) with a low risk of lymph node metastasis (T1a ≤2 cm, without ulcers). This single-arm confirmatory trial evaluated the efficacy an...

    Noriaki Hasuike, Hiroyuki Ono, Narikazu Boku, Junki Mizusawa in Gastric Cancer (2018)

  4. No Access

    Article

    Additional surgery for non-curative resection after endoscopic submucosal dissection for gastric cancer: a retrospective analysis of 200 cases

    Endoscopic submucosal dissection is recommended for early gastric cancer with a low risk of lymph node metastasis. When the pathological findings do not meet the curative criteria; then, an additional gastrect...

    Hideki Sunagawa, Takahiro Kinoshita, Akio Kaito, Hidehito Shibasaki in Surgery Today (2017)

  5. No Access

    Reference Work Entry In depth

    Lugol-Unstained Lesion

    Kazuhiro Kaneko in Encyclopedia of Cancer (2017)

  6. Article

    Open Access

    Natural history of superficial head and neck squamous cell carcinoma under scheduled follow-up endoscopic observation with narrow band imaging: retrospective cohort study

    The incidence rate has been increasing for superficial head and neck squamous cell carcinoma (HNSCC) discovered through surveillance endoscopic study using narrow band imaging (NBI), a procedure mainly used fo...

    Hiroshi Nakamura, Tomonori Yano, Satoshi Fujii, Tomohiro Kadota in BMC Cancer (2016)

  7. No Access

    Article

    Extra-luminal detection of assumed colonic tumor site by near-infrared laparoscopy

    Localization of colorectal tumors during laparoscopic surgery is generally performed by tattooing into the submucosal layer of the colon. However, faint and diffuse tattoos may lead to difficulties in recogniz...

    Tamotsu Zako, Masaaki Ito, Hiroshi Hyodo, Miya Yoshimoto in Surgical Endoscopy (2016)

  8. No Access

    Article

    Endoscopic submucosal resection with a ligation device for the treatment of duodenal neuroendocrine tumors

    Endoscopic submucosal resection with a ligation device (ESMR-L) is effective for rectal neuroendocrine tumors (NETs); however, its effectiveness for duodenal NETs is unclear. This study evaluated the efficacy ...

    Shozo Osera, Yasuhiro Oono, Hiroaki Ikematsu, Tomonori Yano in Surgical Endoscopy (2016)

  9. Article

    Open Access

    Local efficacy and survival outcome of salvage endoscopic therapy for local recurrent lesions after definitive chemoradiotherapy for esophageal cancer

    Salvage endoscopic therapy (SET), such as endoscopic mucosal resection (EMR) and photodynamic therapy (PDT), is a less-invasive treatment for local failure at the primary site after chemoradiotherapy (CRT) for...

    Ken Hatogai, Tomonori Yano, Takashi Kojima, Masakatsu Onozawa in Radiation Oncology (2016)

  10. No Access

    Article

    Peritonitis related to percutaneous endoscopic gastrostomy using the direct method for cancer patients

    Percutaneous endoscopic gastrostomy (PEG) using the direct method is generally indicated for cancer patients. However, there are little available data about peritonitis related to this method. The aim of this...

    Shozo Osera, Tomonori Yano, Tomoyuki Odagaki, Yasuhiro Oono in Surgical Endoscopy (2015)

  11. No Access

    Article

    Usefulness of narrow-band imaging with dual-focus magnification for differential diagnosis of small colorectal polyps

    Many authors have already reported the usefulness of narrow-band imaging (NBI) for the differential diagnosis of non-neoplastic and neoplastic colorectal lesions. However, it is not clear whether magnification...

    Hiroaki Ikematsu, Takahisa Matsuda, Shozo Osera, Maomi Imajoh in Surgical Endoscopy (2015)

  12. No Access

    Living Reference Work Entry In depth

    Lugol-Unstained Lesion

    Kazuhiro Kaneko in Encyclopedia of Cancer

  13. No Access

    Article

    Clinicopathological differences of laterally spreading tumors arising in the colon and rectum

    Laterally spreading tumors (LST) have been recognized worldwide. The aim of our retrospective study was to evaluate the clinicopathological differences of LST arising in the colon and rectum.

    Hideaki Miyamoto, Hiroaki Ikematsu in International Journal of Colorectal Disease (2014)

  14. No Access

    Chapter and Conference Paper

    Development of Novel Endoscope with NIR Camera Using Real-time Video Composite Method

    Recently, a near-infrared (NIR) Fluorescence Biomedical Imaging (FBI) attracts increasing attention from many researchers. The light wavelength region in 1000 nm to 1700 nm has been known to be a “biological w...

    Masayuki Watanabe, Hiroshi Takemura in The 15th International Conference on Biome… (2014)

  15. Article

    Open Access

    Morphological change of a laterally spreading rectal tumor over a short period

    Laterally spreading tumors (LSTs) are generally defined as superficial lesions ≥10 mm in diameter that typically extend laterally rather than vertically along the colonic wall. LSTs are usually categorized int...

    Hideaki Miyamoto, Yasuhiro Oono, Kuang-l Fu, Hiroaki Ikematsu in BMC Gastroenterology (2013)

  16. No Access

    Article

    Endoscopic balloon dilatation for benign fibrotic strictures after curative nonsurgical treatment for esophageal cancer

    Endoscopic balloon dilatation (EBD) is performed to treat strictures after esophagectomy. However, little is known about using EBD for benign strictures that occur after nonsurgical treatments for esophageal c...

    Yusuke Yoda, Tomonori Yano, Kazuhiro Kaneko, Shinya Tsuruta in Surgical Endoscopy (2012)

  17. No Access

    Article

    The impact of narrow band imaging for colon polyp detection: a multicenter randomized controlled trial by tandem colonoscopy

    Previous studies have yielded conflicting results on the adenoma detection rate with narrow band imaging (NBI) compared with white light imaging (WLI). To overcome the confounding factors of these studies, we ...

    Hiroaki Ikematsu, Yutaka Saito, Shinji Tanaka, Toshio Uraoka in Journal of Gastroenterology (2012)

  18. No Access

    Article

    Evaluation of complications related to therapeutic colonoscopy using the bipolar snare

    The complications with therapeutic colonoscopy reported to date have been associated with the monopolar snare, and the frequency of complications related to use of the bipolar snare is uncertain. This study ai...

    Tsutomu Saraya, Hiroaki Ikematsu, Kuang I. Fu, Chihiro Tsunoda in Surgical Endoscopy (2012)

  19. No Access

    Reference Work Entry In depth

    Lugol Unstained Lesion

    Kazuhiro Kaneko in Encyclopedia of Cancer (2011)

  20. Article

    Open Access

    Efficacy of capillary pattern type IIIA/IIIB by magnifying narrow band imaging for estimating depth of invasion of early colorectal neoplasms

    Capillary patterns (CP) observed by magnifying Narrow Band Imaging (NBI) are useful for differentiating non-adenomatous from adenomatous colorectal polyps. However, there are few studies concerning the effecti...

    Hiroaki Ikematsu, Takahisa Matsuda, Fabian Emura, Yutaka Saito in BMC Gastroenterology (2010)

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