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Article
Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers
More than 20 genetic loci have been associated with risk for Alzheimer’s disease (AD), but reported genome-wide significant loci do not account for all the estimated heritability and provide little information...
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Article
Open AccessRole of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans
A recent study found a significant increase of ABCA7 loss-of-function variants in Alzheimer’s disease (AD) cases compared to controls. Some variants were located on noncoding regions, but it was demonstrated that...