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  1. Article

    Open Access

    Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

    The genetic architecture of Parkinson’s Disease (PD) is complex and not completely understood. Multiple genetic studies to date have identified multiple causal genes and risk loci. Nevertheless, most of the ex...

    Laura Ibanez, Umber Dube, Benjamin Saef, John Budde, Kathleen Black in BMC Neurology (2017)

  2. Article

    Open Access

    Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40

    Alzheimer’s disease (AD) pathology appears several years before clinical symptoms, so identifying ways to detect individuals in the preclinical stage is imperative. The cerebrospinal fluid (CSF) Tau/Aβ42 ratio is...

    Yuetiva Deming, Kathleen Black, David Carrell, Yefei Cai in BMC Neurology (2016)