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  1. Article

    Open Access

    Multimodal immunogenomic biomarker analysis of tumors from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab

    We report herein an exploratory biomarker analysis of refractory tumors collected from pediatric patients before atezolizumab therapy (iMATRIX-atezolizumab, NCT02541604

    Arash Nabbi, Arnavaz Danesh, Osvaldo Espin-Garcia, Stephanie Pedersen… in Nature Cancer (2023)

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  2. Article

    Open Access

    MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis

    Many cancer genes form mutation hotspots that disrupt their functional domains or active sites, leading to gain- or loss-of-function. We propose a mutation set enrichment analysis (MSEA) implemented by two nov...

    Peilin Jia, Quan Wang, Qingxia Chen, Katherine E Hutchinson, William Pao… in Genome Biology (2014)

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