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Article
Die analplastische Rekonstruktion nach Ferguson – eine seltene Indikation zur Wiederherstellung des Analkanals
Berichtet wird über die seltene Indikation zur analplastischen Rekonstruktion nach Ferguson bei einem jungen, HIV-infizierten Mann mit narbig verschlossenem Analkanal nach Operation und Bestrahlung eines anale...
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Article
The salt-wasting phenotype of EAST syndrome, a disease with multifaceted symptoms linked to the KCNJ10 K+ channel
Mutations in the K+ channel gene KCNJ10 (Kir4.1) cause the autosomal recessive EAST syndrome which is characterized by epilepsy, ataxia, sensorineural deafness, and a salt-wasting tubulopathy. The renal salt-wast...
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Article
Musiktherapie hilft bei akuter psychotischer Episode
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Article
The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus
Kaposi's sarcoma–associated herpesvirus (KSHV) can infect endothelial cells, leading to the development of Kaposi's sarcoma in some individuals. The mechanisms underlying cell entry by KSHV are not fully eluci...
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Article
Bleaching of colored whey and milk by a multiple-enzyme system
Carotenoids are broadly used to enhance the color of cheese types like Cheddar and Gouda. While ∼80 % of the colorants are transferred into the cheese, the rest remains in the whey and impedes its commercial u...
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Reference Work Entry In depth
Dementia Quality of Life Instrument
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Reference Work Entry In depth
Clinical Dementia Rating Scale
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Article
Open AccessPylorus preserving loop duodeno-enterostomy with sleeve gastrectomy - preliminary results
Bariatric operations mostly combine a restrictive gastric component with a rerouting of the intestinal passage. The pylorus can thereby be alternatively preserved or excluded. With the aim of performing a “pyl...
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Article
Open AccessTargeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model
Expression and activation of the cMET receptor have been implicated in tumor progression and resistance to chemotherapy in human pancreatic cancer. In this regard we assessed the effects of targeting cMET in p...
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Article
Heart rate recovery and aerobic endurance capacity in cancer survivors: interdependence and exercise-induced improvements
Whilst evidence supports beneficial effects of exercise on heart rate variability in cancer patients, its impact on heart rate recovery (HRR) and possible associations of exercise capacity and HRR have not yet...
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Article
Open AccessApplying the Analytic Hierarchy Process in healthcare research: A systematic literature review and evaluation of reporting
The Analytic Hierarchy Process (AHP), developed by Saaty in the late 1970s, is one of the methods for multi-criteria decision making. The AHP disaggregates a complex decision problem into different hierarchica...
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Article
Open AccessNeuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway
Brain development requires a fine-tuned copper homoeostasis. Copper deficiency or excess results in severe neuro-pathologies. We demonstrate that upon neuronal differentiation, cellular demand for copper incre...
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Article
Open AccessShort-lived mammals (shrew, mouse) have a less robust metal-responsive transcription factor than humans and bats
Non-essential “heavy” metals such as cadmium tend to accumulate in an organism and thus are a particular threat for long-lived animals. Here we show that two unrelated, short-lived groups of mammals (rodents a...
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Article
Open AccessComparison of different approaches applied in Analytic Hierarchy Process – an example of information needs of patients with rare diseases
The Analytic Hierarchy Process (AHP) is increasingly used to measure patient priorities. Studies have shown that there are several different approaches to data acquisition and data aggregation. The aim of this...
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Article
Open AccessMeasuring patients’ priorities using the Analytic Hierarchy Process in comparison with Best-Worst-Scaling and rating cards: methodological aspects and ranking tasks
Identifying patient priorities and preference measurements have gained importance as patients claim a more active role in health care decision making. Due to the variety of existing methods, it is challenging ...
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Chapter and Conference Paper
Analysis of Sound Localization Data Generated by the Extended Mainzer Kindertisch
In this paper, we analyze data generated by the extended Mainzer Kindertisch (ERKI setup). The setup uses five loudspeakers to generate 32 virtual sound sources which are ordered in an half circle. It is a new te...
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Chapter
Personalmanagement im Automobilhandel im Kontext der Elektromobilität
Positioniert sich der Automobilhandel im Kontext der Elektromobilität als ganzheitlicher Lösungsanbieter, erfordert dies ein geeignetes Konzept für das Personalmanagement. In diesem Beitrag wird untersucht, we...
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Article
A semiquantitative MRI-Score can predict loss of lung function in patients with cystic fibrosis: Preliminary results
To evaluate the applicability of a semiquantitative MRI scoring system (MR-CF-S) as a prognostic marker for clinical course of cystic fibrosis (CF) lung disease.
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Article
Open AccessProtocol for the “Chemobrain in Motion – study” (CIM – study): a randomized placebo-controlled trial of the impact of a high-intensity interval endurance training on cancer related cognitive impairments in women with breast cancer receiving first-line chemotherapy
Up to 80% of breast cancer patients suffer from Cancer Related Cognitive Impairments (CRCI). Exercise is suggested as a potential supportive care option to reduce cognitive decline in cancer patients. This stu...
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Chapter
Changsha
Die Stadt Changsha ist die Hauptstadt der chinesischen Provinz Hunan. Diese befindet sich im Süden der Volksrepublik und Changsha ist im Nord-Osten der Provinz, am Ufer des **ang Flusses, gelegen. Die Stadt um...
