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Article

Acetylcholine receptor based chemogenetics engineered for neuronal inhibition and seizure control assessed in mice

Epilepsy is a prevalent disorder involving neuronal network hyperexcitability, yet existing therapeutic strategies often fail to provide optimal patient outcomes. Chemogenetic approaches, where exogenous recep...

Quynh-Anh Nguyen, Peter M. Klein, Cheng **e, Katelyn N. Benthall… in Nature Communications (2024)