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Qualifying and quantifying minimal hepatic encephalopathy
Minimal hepatic encephalopathy is the term applied to the neuropsychiatric status of patients with cirrhosis who are unimpaired on clinical examination but show alterations in neuropsychological tests explorin...
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Psychometric tests for diagnosing minimal hepatic encephalopathy
While it is consensus that minimal hepatic encephalopathy (mHE) has significant impact on a patient’s daily living, and thus should be diagnosed and treated, there is no consensus about the optimal diagnostic ...
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Introduction
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Hepatitis C virus infection and the brain
There is growing evidence that hepatitis C virus (HCV)-infection may affect the brain. About half of the HCV-infected patients complain of chronic fatigue irrespective of their stage of liver disease or virus ...
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Introduction
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The treatment of hepatic encephalopathy
Current recommendations for the treatment of hepatic encephalopathy are based, to a large extent, on open or uncontrolled trials, undertaken in very small numbers of patients. In consequence, there is ongoing ...
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Article
Attention, Memory, and Cognitive Function in Hepatic Encephalopathy
Deficits in attention and arousal play a major role in the clinical presentation of hepatic encephalopathy. Attention deficits arealso the main components of minimal hepatic encephalopathy. The present paper s...
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Preface
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Article
Functional Imaging of the Brain in Patients with Liver Cirrhosis
Brain imaging techniques have provided substantial insight into the pathophysiology of hepatic encephalopathy (HE). Magnetic resonance imaging gave hint to the fact that there is an increased deposition of man...
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Correlations Between Cerebral Glucose Metabolism and Neuropsychological Test Performance in Nonalcoholic Cirrhotics
Many cirrhotics have abnormal neuropsychological test scores. To define the anatomical–physiological basis for encephalopathy in nonalcoholic cirrhotics, we performed resting-state fluorodeoxyglucose positron ...
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Attention Deficits in Minimal Hepatic Encephalopathy
Minimal hepatic encephalopathy (HE) is characterized by a decrease of psychomotor speed, and deficits in visual perception, visuo-spatial orientation, and visuo-constructive abilities. Attention deficits have ...
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Altered Striatal Dopamine D2 Receptor Density and Dopamine Transport in a Patient with Hepatic Encephalopathy
A patient suffering from liver cirrhosis presented with a bradykinetic-rigid syndrome suspected as Parkinson's disease. A detailed work-up of the case revealed hepatic encephalopathy as the cause of the neurol...
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Article
Altered striatal dopamine D2 receptor density and dopamine transport in a patient with hepatic encephalopathy
A patient suffering from liver cirrhosis presented with a bradykinetic-rigid syndrome suspected as Parkinson's disease. A detailed work-up of the case revealed hepatic encephalopathy as the cause of the neurol...
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Article
Pathophysiology of Hepatic Encephalopathy: Results of the Hannover Consensus Conference
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The Basal Ganglia and Portal-Systemic Encephalopathy
Despite decades of research, the pathogenesis of portal-systemic encephalopathy (PSE) remains puzzling. Current hypotheses on the pathophysiology of PSE usually deal with metabolic toxins like ammonia or distu...