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  1. Article

    Open Access

    Reduced microglia activity in patients with long-term immunosuppressive therapy after liver transplantation

    Calcineurin inhibitors (CNI) can cause long-term impairment of brain function. Possible pathomechanisms include alterations of the cerebral immune system. This study used positron emission tomography (PET) ima...

    Meike Dirks, Ralph Buchert in European Journal of Nuclear Medicine and M… (2021)

  2. Article

    Open Access

    Reliable quantification of 18F-GE-180 PET neuroinflammation studies using an individually scaled population-based input function or late tissue-to-blood ratio

    Tracer kinetic modeling of tissue time activity curves and the individual input function based on arterial blood sampling and metabolite correction is the gold standard for quantitative characterization of mic...

    Ralph Buchert, Meike Dirks in European Journal of Nuclear Medicine and M… (2020)

  3. No Access

    Article

    Hepatic encephalopathy after treatment with temozolomide

    Temozolomide in combination with radiation has been in use for more than 5 years for the therapy of glioblastoma. Known adverse effects concerning the gastrointestinal system are elevation of liver enzymes. We...

    Annemarie Goldbecker, Anita Blanka Tryc, Peter Raab in Journal of Neuro-Oncology (2011)