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  1. Article

    Open Access

    Assessment of associations between neutrophil extracellular trap biomarkers in blood and thrombi in acute ischemic stroke patients

    Inflammation including immunothrombosis by neutrophil extracellular traps (NETs) has important implications in acute ischemic stroke and can affect reperfusion status, susceptibility to stroke associated infec...

    Tristan Baumann, Nicole de Buhr, Nicole Blume in Journal of Thrombosis and Thrombolysis (2024)

  2. Article

    Open Access

    Reduced microglia activity in patients with long-term immunosuppressive therapy after liver transplantation

    Calcineurin inhibitors (CNI) can cause long-term impairment of brain function. Possible pathomechanisms include alterations of the cerebral immune system. This study used positron emission tomography (PET) ima...

    Meike Dirks, Ralph Buchert in European Journal of Nuclear Medicine and M… (2021)

  3. Article

    Open Access

    Reliable quantification of 18F-GE-180 PET neuroinflammation studies using an individually scaled population-based input function or late tissue-to-blood ratio

    Tracer kinetic modeling of tissue time activity curves and the individual input function based on arterial blood sampling and metabolite correction is the gold standard for quantitative characterization of mic...

    Ralph Buchert, Meike Dirks in European Journal of Nuclear Medicine and M… (2020)

  4. Article

    Open Access

    Septal total atrial conduction time for prediction of atrial fibrillation in embolic stroke of unknown source: a pilot study

    Subclinical atrial fibrillation (AF) is the underlying cause in a relevant part of patients with embolic stroke of unknown source (ESUS). This pilot study aims to identify novel echocardiographic parameters pr...

    Jan-Thorben Sieweke, Saskia Biber, Karin Weissenborn in Clinical Research in Cardiology (2020)

  5. No Access

    Article

    ADAMTS13 activity is associated with early neurological improvement in acute ischemic stroke patients treated with intravenous thrombolysis

    Although intravenous thrombolysis (IVT) with recombinant tissue-plasminogen-activator represents a highly effective treatment in acute ischemic stroke patients, not every patient benefits. We hypothesized that...

    Anne-Sophie Putzer, Hans Worthmann in Journal of Thrombosis and Thrombolysis (2020)