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  1. Article

    Open Access

    Combination therapies utilizing neoepitope-targeted vaccines

    Clinical successes have been achieved with checkpoint blockade therapy, which facilitates the function of T cells recognizing tumor-specific mutations known as neoepitopes. It is a reasonable hypothesis that t...

    Karin L. Lee, Jeffrey Schlom, Duane H. Hamilton in Cancer Immunology, Immunotherapy (2021)

  2. No Access

    Chapter

    Plant Virus-Based Nanotechnologies

    Nanoscale engineering is revolutionizing disease detection and prevention. Viruses have made a remarkable contribution to these developments because they can function as prefabricated nanoparticles that have n...

    Amy M. Wen, Karin L. Lee, Nicole F. Steinmetz in Women in Nanotechnology (2020)

  3. No Access

    Protocol

    Genetic Engineering and Chemical Conjugation of Potato Virus X

    Here we report the genetic engineering and chemical modification of potato virus X (PVX) for the presentation of various peptides, proteins, and fluorescent dyes, or other chemical modifiers. Three different w...

    Karin L. Lee, Kerstin Uhde-Holzem, Rainer Fischer in Virus Hybrids as Nanomaterials (2014)