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  1. Article

    Open Access

    Design, structure and plasma binding of ancestral β-CoV scaffold antigens

    We report the application of ancestral sequence reconstruction on coronavirus spike protein, resulting in stable and highly soluble ancestral scaffold antigens (AnSAs). The AnSAs interact with plasma of patien...

    David Hueting, Karen Schriever, Rui Sun, Stelios Vlachiotis… in Nature Communications (2023)

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