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Open AccessDesign, structure and plasma binding of ancestral β-CoV scaffold antigens
We report the application of ancestral sequence reconstruction on coronavirus spike protein, resulting in stable and highly soluble ancestral scaffold antigens (AnSAs). The AnSAs interact with plasma of patien...
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Article
Open AccessMetabolite interactions in the bacterial Calvin cycle and implications for flux regulation
Metabolite-level regulation of enzyme activity is important for microbes to cope with environmental shifts. Knowledge of such regulations can also guide strain engineering for biotechnology. Here we apply limi...
