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Article
Open AccessComparing genomes recovered from time-series metagenomes using long- and short-read sequencing technologies
Over the past years, sequencing technologies have expanded our ability to examine novel microbial metabolisms and diversity previously obscured by isolation approaches. Long-read sequencing promises to revolut...
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Article
Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle
One of the most abundant sources of organic carbon in the ocean is glycolate, the secretion of which by marine phytoplankton results in an estimated annual flux of one petagram of glycolate in marine environments
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Article
Allgemeinmedizinische Lehre und Berufswunsch im Berliner Modellstudiengang
An der Berliner Charité sind alle Studierenden im Modellstudiengang immatrikuliert. Erstmalig wurden nun Studierende des 10. Semesters nach ihrer Erfahrung mit der Allgemeinmedizinischen Lehre und den Dozieren...
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Article
Open AccessCloning and characterization of an adenoviral vector for highly efficient and doxycycline – suppressible expression of bioactive human single – chain interleukin 12 in colon cancer
Interleukin-12 (IL-12) is well characterized to induce cellular antitumoral immunity by activation of NK-cells and T-lymphocytes. However, systemic administration of recombinant human IL-12 resulted in severe ...