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  1. Article

    Open Access

    Tidal volume significantly affects oxygenation in healthy pigs during high-frequency oscillatory ventilation compared to conventional ventilation

    The role of high-frequency oscillatory ventilation (HFOV) has long been debated. Numerous studies documented its benefits, whereas several more recent studies did not prove superiority of HFOV over protective ...

    Karel Roubík, Jakub Ráfl, Martin Rožánek, Petr Kudrna in BioMedical Engineering OnLine (2022)

  2. No Access

    Chapter and Conference Paper

    Breathing Experiments into the Simulated Avalanche Snow: Medical and Technical Issues of the Outdoor Breathing Trials

    Avalanche burials represent one of the most dangerous risks associated with winter activities in the mountains. Asphyxiation occurs as a consequence of blocked airways; or, due to a severe hypoxia and hypercap...

    Lenka Horáková, Karel Sýkora in World Congress on Medical Physics and Biom… (2019)

  3. No Access

    Chapter and Conference Paper

    Design and Demonstration of a Complex Neonatal Physiological Model for Testing of Novel Closed-Loop Inspired Oxygen Fraction Controllers

    Recently published clinical trials document that manual control of oxygen fraction in the inspiratory gas in neonates is not prompt enough to react to the rapidly changing physiological status of a neonate. As...

    Jakub Rafl, Thomas E. Bachman in World Congress on Medical Physics and Biom… (2019)

  4. No Access

    Chapter and Conference Paper

    Center of Ventilation—Methods of Calculation Using Electrical Impedance Tomography and the Influence of Image Segmentation

    Electrical impedance tomography (EIT) is a promising non-invasive, radiation-free imaging modality. Using EIT-derived index Center of ventilation (CoV), ventral-to-dorsal shifts in distribution of lung ventila...

    Vladimir Sobota, Karel Roubik in XIV Mediterranean Conference on Medical an… (2016)

  5. No Access

    Chapter and Conference Paper

    Design and Evaluation of a System Assuring Spontaneous Breathing in Patients Connected to a High-Frequency Oscillatory Ventilator

    Patients connected to a high-frequency oscillatory ventilator should be paralysed or highly sedated so that the ventilator is able to work. The aim of the study is to design a special “Demand Flow System” allo...

    Karel Roubik, Marc van Heerde in 5th European Conference of the Internation… (2012)