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    Article

    Characterizing Enoxaparin’s Population Pharmacokinetics to Guide Dose Individualization in the Pediatric Population

    Pediatric dosing of enoxaparin was derived based on extrapolation of the adult therapeutic range to children. However, a large fraction of children do not achieve therapeutic anticoagulation with initial dosin...

    Fernando O. Carreño, Jacqueline G. Gerhart, Victória E. Helfer in Clinical Pharmacokinetics (2024)

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    Article

    Risk of in-hospital Deterioration for Children with Single Ventricle Physiology

    Children with single ventricle physiology (SV) are at high risk of in-hospital morbidity and mortality. Identifying children at risk for deterioration may allow for earlier escalation of care and subsequently ...

    Henry P. Foote, Grace S. Lee, Carla Dominguez Gonzalez in Pediatric Cardiology (2023)

  3. Article

    Open Access

    Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling

    While one in five children in the USA are now obese, and more than three-quarters receive at least one drug during childhood, there is limited dosing guidance for this vulnerable patient population. Physiologi...

    Jacqueline G. Gerhart, Fernando O. Carreño, Andrea N. Edginton in Clinical Pharmacokinetics (2022)

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    Article

    Patterns of phlebotomy blood loss and transfusions in extremely low birth weight infants

    Characterize frequency and volume of blood draws and transfusions in extremely low birth weight infants in the first 10 weeks of life.

    Mihai Puia-Dumitrescu, David T. Tanaka, Tracy G. Spears in Journal of Perinatology (2019)

  5. Article

    Correction to: Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings

    The original version of this article unfortunately contained a mistake. The subtitle “A Midwest Pediatric Nephrology Consortium (MWPNC) study” was missing. The correct title including subtitle is given above.

    Jonathan H. Pelletier, Karan R. Kumar, Rachel Engen, Adam Bensimhon in Pediatric Nephrology (2019)

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    Article

    Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings

    Steroid-resistant nephrotic syndrome (SRNS) due to focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) is a leading cause of end-stage kidney disease in children. Recurrence of primary d...

    Jonathan H. Pelletier, Karan R. Kumar, Rachel Engen, Adam Bensimhon in Pediatric Nephrology (2018)