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  1. No Access

    Article

    Trends in the incidence of urothelial carcinoma in Taiwan after the ban on aristolochic acid-containing Chinese herbal preparations, 2001–2018: a national population-based cohort study

    Urothelial carcinoma (UC) of the bladder (BUC) and the upper urinary tract (UTUC) are the two most common UCs. The incidence of UTUC in Taiwan is the highest worldwide. Aristolochic acid (AA) was identified as...

    Cheng-I. Liao, Hua-Chang Fang, Po-Tsang Lee in Journal of Cancer Research and Clinical On… (2023)

  2. Article

    Open Access

    Psychometric properties and measurement invariance of Short-Form Life Attitude Inventory for hospital staff

    The life attitude of health care workers can deeply influence the quality of care. Examining the performance of the Short-Form Life Attitude Inventory (SF-LAI), this study analyzes the factorial structure, rel...

    Kang-Ju Chou, Ying-Yao Cheng, Hua-Chang Fang, Fu-Zong Wu in BMC Medical Education (2022)

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    Article

    Efficacy and Safety of Direct Oral Anticoagulants vs Warfarin in Patients with Chronic Kidney Disease and Dialysis Patients: A Systematic Review and Meta-Analysis

    Systematic reviews and meta-analyses of direct oral anticoagulants (DOACs) for patients with chronic kidney disease (CKD) or dialysis patients are lacking. We aimed to compare the efficacy and safety of DOACs ...

    Hsin-Yu Chen, Shih-Hsiang Ou, Chien-Wei Huang, Po-Tsang Lee in Clinical Drug Investigation (2021)

  4. Article

    Open Access

    Evaluation of the association of Wnt signaling with coronary artery calcification in patients on dialysis with severe secondary hyperparathyroidism

    Patients with end-stage renal disease have a higher risk of death from cardiovascular events, which can be mainly attributed to coronary artery calcification (CAC). Wnt signaling is involved in vascular develo...

    Tzung-Yo Ho, Nai-Ching Chen, Chih-Yang Hsu, Chien-Wei Huang, Po-Tsang Lee in BMC Nephrology (2019)

  5. Article

    Open Access

    The relation of location-specific epicardial adipose tissue thickness and obstructive coronary artery disease: systemic review and meta-analysis of observational studies

    There is growing evidence about the importance of epicardial adiposity on cardiometabolic risk. However, the relation of location-specific epicardial adipose tissue (EAT) thickness to coronary atherosclerotic ...

    Fu-Zong Wu, Kang-Ju Chou, Yi-Luan Huang, Ming-Ting Wu in BMC Cardiovascular Disorders (2014)

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    Article

    Preventing contrast-induced nephropathy in patients with baseline renal dysfunction undergoing coronary angiography

    Although contrast-induced nephropathy (CIN) is usually self-limited, it may cause permanent renal injury and even lead to long-term dialysis in patients with preexisting renal impairment. Cardiologists face a ...

    Po-Tsang Lee, Kang-Ju Chou, Hua-Chang Fang in Current Treatment Options in Cardiovascula… (2009)

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    Article

    Tamoxifen-Induced Increases in Cytoplasmic Free Ca2+ Levels in Human Breast Cancer Cells

    Tamoxifen has been shown to increase cytoplasmic free Ca2+ levels [Ca2+]i in renal tubular cells and bladder cancer cells, and to alter Ca2+ signaling in MCF-7 breast cancer cells. The present study examined the ...

    Hong-Tai Chang, Jong-Khing Huang, Jue-Long Wang in Breast Cancer Research and Treatment (2002)

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    Article

    Novel action of lignans isolated from Hernandia nymphaeifolia on Ca2+ signaling in human neutrophils

    The effects of five lignans (epi-aschantin, epi-magnolin, epi-yangambin, deoxypodophyllotoxin, yatein) isolated from Hernandia nymphaeifolia (Presl.) Kubitzki (Hernandiaceae) on intracellular Ca2+ levels ([Ca2+]

    Yu-Ying Chao, Warren Su, Chung-Ren Jan, Ying-Chin Ko in Archives of Toxicology (2002)

  9. No Access

    Article

    Dual action of palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling: activation of extracellular Ca2+ influx and alteration of ATP- and bradykinin-induced Ca2+ responses in Madin Darby canine kidney cells

    The effect of the phospholipase A2 inhibitor palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling in Madin Darby canine kidney (MDCK) cells was examined using fura-2 as the fluorescent Ca2+ indicator. At...

    Chung-Ren Jan, Kang-Ju Chou, Kam Chung Lee, Jue-Long Wang in Archives of Toxicology (2000)