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  1. Article

    Open Access

    Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication

    Patients with bilateral primary aldosteronism (PA) generally are treated with antihypertensive drugs, but optimal treatment for patients with complications due to refractory hypertension has not been establish...

    Seiji Hoshi, Akifumi Onagi, Ryo Tanji, Ruriko Honda-Takinami in BMC Endocrine Disorders (2023)

  2. Article

    Open Access

    The prevalence and predictive factors of nocturnal polyuria in Japanese patients with nocturia: a multicentral retrospective cohort study

    The aims of this study were to determine the prevalence and predictors of nocturnal polyuria (NP) in Japanese patients. This multicentral, observational study enrolled patients with the chief complaint of noct...

    Koji Iinuma, Yoshinori Nishino, Kanako Matsuoka, Tatsuya Ihara in Scientific Reports (2023)

  3. Article

    Open Access

    Role of puboperinealis and rectourethralis muscles as a urethral support system to maintain urinary continence after robot-assisted radical prostatectomy

    The present study investigated the role of a urethral support system to maintain urinary continence after robot-assisted radical prostatectomy (RARP), with a focus on pelvic floor muscles, such as the puboperi...

    Masao Kataoka, Satoru Meguro, Ryo Tanji, Akifumi Onagi in Scientific Reports (2023)

  4. No Access

    Article

    Usefulness of the mayo adhesive probability score as a predictive factor for renal function deterioration after partial nephrectomy: a retrospective case–control study

    Whether the Mayo adhesive probability score, an index of the perinephric fat environment, could be a predictive factor for renal function deterioration after partial nephrectomy was investigated.

    Junya Hata, Yuta Matsuoka, Akifumi Onagi in International Urology and Nephrology (2021)

  5. No Access

    Article

    The effect of β3-adrenoceptor gene polymorphisms on lower urinary tract function in males

    To clarify the role of Trp64Arg polymorphisms of the gene encoding the β3-adrenoceptor for lower urinary tract function in males, the present study investigated the association between the Trp64Arg polymorphisms ...

    Nobuhiro Haga, Yu Okabe, Takeshi Miyazaki, Kazuna Tsubouchi in World Journal of Urology (2021)

  6. Article

    Open Access

    Tetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability

    This study aimed to investigate the influence of chronic ischemia on nitric oxide biosynthesis in the bladder and the effect of administering tetrahydrobiopterin (BH4), a cofactor for endothelial nitric oxide ...

    Hidenori Akaihata, Junya Hata, Ryo Tanji, Ruriko Honda-Takinami in Scientific Reports (2020)

  7. No Access

    Article

    Transient renal dysfunction due to rhabdomyolysis after robot-assisted radical prostatectomy

    The aim of the present study was to investigate whether renal dysfunction following rhabdomyolysis occurs after robot-assisted radical prostatectomy (RARP), and to investigate the factors related to rhabdomyol...

    Akifumi Onagi, Nobuhiro Haga, Ryo Tanji in International Urology and Nephrology (2020)

  8. No Access

    Article

    The preoperative pad test as a predictor of urinary incontinence and quality of life after robot-assisted radical prostatectomy: a prospective, observational, clinical study

    To assess whether the preoperative 1-h pad test could predict postoperative urinary incontinence and quality of life after robot-assisted radical prostatectomy.

    Yoshimasa Kurimura, Nobuhiro Haga in International Urology and Nephrology (2020)

  9. Article

    Open Access

    Complement activation by autoantigen recognition in the growth process of benign prostatic hyperplasia

    The pathophysiology of benign prostatic hyperplasia (BPH) remained unclear. Here, we concentrated on the complement activation in the growth of BPH using a rat model. BPH tissues were harvested from rats after...

    Junya Hata, Takeshi Machida, Kanako Matsuoka, Seiji Hoshi in Scientific Reports (2019)