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  1. Article

    Open Access

    Visfatin (NAMPT) affects global gene expression in porcine anterior pituitary cells during the mid-luteal phase of the oestrous cycle

    The pituitary belongs to the most important endocrine glands involved in regulating reproductive functions. The proper functioning of this gland ensures the undisturbed course of the oestrous cycle and affects...

    Kamil Dobrzyn, Grzegorz Kopij, Marta Kiezun in Journal of Animal Science and Biotechnology (2024)

  2. Article

    Open Access

    In vitro effect of visfatin on endocrine functions of the porcine corpus luteum

    Previously, we demonstrated the expression of visfatin in porcine reproductive tissues and its effect on pituitary endocrinology. The objective of this study was to examine the visfatin effect on the secretion...

    Ewa Mlyczyńska, Edyta Rytelewska, Ewa Zaobidna in Scientific Reports (2024)

  3. Article

    Open Access

    Visfatin impact on the proteome of porcine luteal cells during implantation

    Visfatin (VIS) is a hormone belonging to the adipokines’ group secreted mainly by the adipose tissue. VIS plays a crucial role in the control of energy homeostasis, inflammation, cell differentiation, and angi...

    Grzegorz Kopij, Marta Kiezun, Marlena Gudelska, Kamil Dobrzyn in Scientific Reports (2024)

  4. Article

    Open Access

    Apelin-13 modulates the endometrial transcriptome of the domestic pig during implantation

    The peri-implantation period is a critical time during pregnancy that mostly defines the overall litter size. Most authors agree that the highest percentage of embryo mortality occurs during this time. Despite...

    Kamil Dobrzyn, Marta Kiezun, Grzegorz Kopij, Barbara Zarzecka in BMC Genomics (2024)

  5. Article

    Open Access

    Plasma level of omentin-1, its expression, and its regulation by gonadotropin-releasing hormone and gonadotropins in porcine anterior pituitary cells

    Omentin-1 (OMNT1) is an adipokine involved in the regulation of energy metabolism, insulin sensitivity, and reproduction. The present study was the first to investigate the plasma levels and expression of OMNT...

    Natalia Respekta, Karolina Pich, Ewa Mlyczyńska, Kamil Dobrzyń in Scientific Reports (2023)

  6. Article

    Open Access

    Visfatin in the porcine pituitary gland: expression and regulation of secretion during the oestrous cycle and early pregnancy

    Visfatin is a multifunctional protein which, besides the control of energy homeostasis, seems to be also involved in the regulation of female fertility through the influence on the endocrine hypothalamus-pitui...

    Karolina Szymanska, Ewa Zaobidna, Edyta Rytelewska, Ewa Mlyczynska in Scientific Reports (2023)

  7. Article

    Open Access

    Plasma level and expression of visfatin in the porcine hypothalamus during the estrous cycle and early pregnancy

    Visfatin appears to be an energy sensor involved in the regulation of female fertility, which creates a hormonal link integrating the control of energy homeostasis and reproduction. This study evaluates the ex...

    Tadeusz Kaminski, Marta Kiezun, Ewa Zaobidna, Kamil Dobrzyn in Scientific Reports (2021)

  8. Article

    Open Access

    The in vitro effect of progesterone on the orexin system in porcine uterine tissues during early pregnancy

    Orexin A (OXA) and orexin B (OXB) are hypothalamic-derived peptides that participate in the regulation of energy metabolism, food intake and reproductive function by influencing the hypothalamic-pituitary-ovar...

    Kamil Dobrzyn, Nina Smolinska, Marta Kiezun, Karol Szeszko in Acta Veterinaria Scandinavica (2018)

  9. Article

    Open Access

    The influence of adiponectin on the transcriptomic profile of porcine luteal cells

    Reproductive functions are closely related to nutritional status. Recent studies suggest that adiponectin may be a hormonal link between them. Adiponectin is an adipocytokine, abundantly expressed in adipose t...

    Karol Szeszko, Nina Smolinska, Marta Kiezun in Functional & Integrative Genomics (2016)