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Versatile Therapeutic Potential of Swertia chirayita (Roxb.) H. Karst: A Review
Swertia chirayita (family- Gentianaceae, common name: Chiryatah) is an herb native to temperate Himalayas and Khasi hills of Meghalaya found at an altitude of 1100 m to 3000 m. The whole plant is widely used as a...
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Article
Exploring the potential of Moringa oleifera Lam in skin disorders and cosmetics: nutritional analysis, phytochemistry, geographical distribution, ethnomedicinal uses, dermatological studies and cosmetic formulations
Moringa oleifera Lam. is a pan-tropical plant well known to the ancient world for its extensive therapeutic benefits in the Ayurvedic and Unani medical systems. The ancient world was familiar with this tree, but ...
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Article
Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices
In recent year, the research of transdermal drug delivery systems has got substantial attention towards the development of microneedles (MNs). This shift has occurred due to multifaceted advantages of MNs as t...
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Article
Advances in nano-based drug delivery systems for the management of cytokine influx-mediated inflammation in lung diseases
Asthma, lung cancer, cystic fibrosis, tuberculosis, acute respiratory distress syndrome, chronic obstructive pulmonary disease, and COVID-19 are few examples of inflammatory lung conditions that cause cytokine...
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Article
Enhancing the oral bioavailability of fisetin: polysaccharide-based self nano-emulsifying spheroids for colon-targeted delivery
Fisetin (FS) is a flavonoid that possesses antioxidant and anti-inflammatory properties against ulcerative colitis. FS shows poor dissolution rate and permeability. An attempt has been made to develop colon-ta...
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Article
Unravelling the success of transferosomes against skin cancer: Journey so far and road ahead
Skin cancer remains one of the most prominent types of cancer. Melanoma and non-melanoma skin cancer are commonly found together, with melanoma being the more deadly type. Skin cancer can be effectively treate...
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Article
Open AccessComparative pharmacokinetic evaluation of nanoparticle-based vs. conventional pharmaceuticals containing statins in attenuating dyslipidaemia
Dyslipidaemia describes the condition of abnormal lipid levels in a person’s bloodstream. Since the 1980s, statin medications have been used to treat dyslipidaemia and other comorbidities, such as stroke risk ...
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Article
Unwinding circular RNA’s role in inflammatory pulmonary diseases
Circular RNAs (circRNAs) have emerged as pivotal regulators of gene expression and cellular processes in various physiological and pathological conditions. In recent years, there has been a growing interest in...
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Article
Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic factors for both ailments. These diseases s...
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Article
Unraveling the role of glial cell line–derived neurotrophic factor in the treatment of Parkinson’s disease
Parkinson’s disease is the second most common neurodegenerative condition with its prevalence projected to 8.9 million individuals globally in the year 2019. Parkinson’s disease affects both motor and certain ...
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Article
Open AccessZerumbone liquid crystalline nanoparticles protect against oxidative stress, inflammation and senescence induced by cigarette smoke extract in vitro
The purpose of this study was to evaluate the potential of zerumbone-loaded liquid crystalline nanoparticles (ZER-LCNs) in the protection of broncho-epithelial cells and alveolar macrophages against oxidative ...
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Article
Unravelling role of crocin for the treatment of Alzheimer’s and Parkinson’s disease: sojourn from food to nanomedicine
Flavonoids have a longstanding tradition of being employed in traditional medicine to improve human health. Crocin has been suggested as a potential candidate for addressing a range of ailments, including neur...
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Article
Polysaccharide-fecal microbiota-based colon-targeted self-nanoemulsifying drug delivery system of curcumin for treating polycystic ovarian syndrome
The gut microbiome is involved in the pathogenesis of many diseases including polycystic ovarian syndrome (PCOS). Modulating the gut microbiome can lead to eubiosis and treatment of various metabolic condition...
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Article
Targeting inflammatory signaling in obsessive compulsive disorder: a promising approach
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder. Approximately, around 2% to 3% percent of the general population experience symptoms of OCD over the course of their lifetime. OCD can lead t...
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Article
Open AccessExploring the influence of the microbiome on the pharmacology of anti-asthmatic drugs
The microbiome is increasingly implicated in playing a role in physiology and pharmacology; in this review, we investigate the literature on the possibility of bacterial influence on the pharmacology of anti-a...
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Reference Work Entry In depth
An Update on Clinical Trials on Synbiotics
Combinations of prebiotics and probiotics are known as “synbiotics,” because certain prebiotic compounds help probiotic bacteria expand. Supplements and specific foods like dairy products, whole grains, and ca...
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Chapter
Application of Artificial Intelligence in NeuroCOVID-19
In the realm of cutting-edge technology, the application of artificial intelligence (AI) emerges as an inspiration of hope and innovation in the field of healthcare. This chapter explores into the applications...
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Reference Work Entry In depth
Advanced Drug Delivery Approaches Containing Synbiotics
Synbiotics have shown various beneficial effects in inflammatory bowel diseases, irritable bowel syndrome, infectious disorders, and diarrheal illnesses. However, the delivery of probiotics to the host intesti...
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Book and Reference Work
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Reference Work Entry In depth
Polysaccharide-Based Nano-delivery Systems for the Treatment of Colorectal Cancer
Use of nano-delivery systems for the treatment of colorectal cancer has been tried successfully for almost all known varieties of such delivery systems. However, the unique property of polysaccharides of resis...
