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  1. No Access

    Article

    Knocking Down PIAS3 Reduces H2O2-induced Oxidative Stress Injury in HT22 Cells

    Oxidative stress is involved in the pathological processes of many neurodegenerative diseases. Protein modification by small ubiquitin-like modifiers (SUMOs) has been implicated in oxidative stress injury. By ...

    Baixue Wang, Wenxin Qian, Kaiyue Chen, Meng Li… in Cell Biochemistry and Biophysics (2024)

  2. No Access

    Article

    Engineering adjacent Fe3C as proton-feeding centers to single Fe sites enabling boosted oxygen reduction reaction kinetics for robust Zn-air batteries at high current densities

    Oxygen reduction reaction (ORR) plays an important role in the next-generation energy storage technologies, whereas it involves the sluggish and complicated proton-coupled electron transfer (PCET) steps that g...

    Canhui Zhang, **ngkun Wang, Kai Song, Kaiyue Chen, Shuixing Dai… in Nano Research (2023)

  3. Article

    Open Access

    Effectiveness of WeChat-group-based parental health education in preventing unintentional injuries among children aged 0–3: randomized controlled trial in Shanghai

    Unintentional injuries to children are a major public health problem. The online social media is a potential way to implement health education for caregivers in online communities. Using WeChat, a free and pop...

    Yuheng Feng, Xueqi Ma, Qi Zhang, Ruo Jiang, Jun Lu, Kaiyue Chen… in BMC Public Health (2022)

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  4. No Access

    Article

    Stress response capacity analysis during aging and possible new insights into aging studies

    The causes and consequences of aging have always been a concern. In recent studies, changes in the stress response capacity of cells during aging were quantitatively analyzed. It was found that aging was accom...

    Kaiyue Chen, Wenting Shen, Ziqing Gao, Chunxiong Luo in Current Genetics (2021)

  5. Article

    Open Access

    Age-dependent decline in stress response capacity revealed by proteins dynamics analysis

    The aging process is regarded as the progressive loss of physiological integrity, leading to impaired biological functions and the increased vulnerability to death. Among various biological functions, stress r...

    Kaiyue Chen, Wenting Shen, Zhiwen Zhang, Fangzheng **ong, Qi Ouyang… in Scientific Reports (2020)

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  6. No Access

    Article

    The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia

    Compromised placentation strongly predisposes to preeclampsia (PE) which is a severe complication of pregnancy. Pregnancy-associated plasma protein-A2 (PAPP-A2) has higher expression in the placenta than in an...

    ** Chen, Kaiyue Chen, Yun Feng, Ci Ren, Wei Li, Juan **ao, Lei Fan… in Hypertension Research (2019)