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  1. No Access

    Article

    Simvastatin ameliorates synaptic plasticity impairment in chronic mild stress-induced depressed mice by modulating hippocampal NMDA receptor

    In our previous study, we showed simvastatin exerts an antidepressant effect and inhibits neuroinflammation. Given the role of synaptic impairment in depression development, we investigate the effect of simvas...

    Xu-Ben Yu, Kai-Long Zhong, Chuang Chen, **g Fu, Fang Chen… in Psychopharmacology (2024)

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    Article

    New views and possibilities of antidiabetic drugs in treating and/or preventing mild cognitive impairment and Alzheimer’s Disease

    Mounting evidence suggests that diabetes mellitus (DM) is associated with mild cognitive impairment (MCI), vascular dementia and Alzheimer’s disease (AD). Biological, clinical and epidemiological data support ...

    Kai Long Zhong, Fang Chen, Hao Hong, Xuan Ke, Yang Ge Lv… in Metabolic Brain Disease (2018)