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Article
Screening for BRCA1 gene mutations by capillary electrophoretic REF-SSCP
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Article
Microencapsulated octreotide pamoate in advanced gastrointestinal and pancreatic cancer: a phase I study
Fourteen patients suffering from advanced colorectal (n = 7), pancreatic (n = 4) or gastric (n = 3) carcinomas received treatment with microencapsulated octreotide pamoate 90 mg i.m. every 4 weeks (n = 4), 160...
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Article
Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis
c-erbB-2 gene amplification and protein over-expression were investigated in 89 primary tumours and 24 metastases from Norwegian breast cancer patients. Amplification occurred in 22.5% of the primary tumours a...
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Article
Colony forming ability of human breast carcinomas: lack of prognostic significance
To study whether colony growth in vitro reflects the prognosis of breast cancer patients, specimens from a total number of 138 patients with primary breast carcinomas were cultivated in the Courtenay-Mills sof...
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Article
Predictive chemosensitivity testing in malignant melanoma: reliable methodology – ineffective drugs
A retrospective and a prospective trial were carried out in patients with malignant melanomas to investigate the predictive value of an in vitro chemosensitivity assay based on the Courtenay and Mills soft aga...
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Article
Cultivation of human breast carcinoma in soft agar. Experience with 237 fresh tumour specimens
A total of 237 breast carcinomas have been studied with the Courtenay-Mills (C-M) soft agar method. Cell yields and plating efficiencies (PE) were recorded after various enzyme treatments. The highest cell yie...
