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Article
Salivary Alpha-Amylase Activity and Mild Cognitive Impairment among Japanese Older Adults: The Toon Health Study
There is growing interest in examining objective markers for early identification and behavioral intervention to prevent dementia and mild cognitive impairment in clinical and community settings.
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Article
A comparison of objective physical activity, muscle strength, and depression among community-dwelling older women living in sloped versus non-sloped environments
To examine the relationship between the living location and outcomes of physical activity level and physical and psychological functioning in older women. The specific aim was to understand the association bet...
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Article
N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties
N-cadherin and HER2/neu were found to be co-expressed in invasive breast carcinomas. To test the contribution of N-cadherin and HER2 in mammary tumor metastasis, we targeted N-cadherin expression in the mammar...
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Article
Endoplasmic reticulum stress response in the rat contusive spinal cord injury model-susceptibility in specific cell types
Focus group study
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Article
p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis
Cell proliferation and invasion are critical for malignant progression, yet how these processes relate to each other and whether they regulate one another during metastasis is unknown. We show that invasivenes...
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Article
N-cadherin regulates mammary tumor cell migration through Akt3 suppression
N-cadherin is a cell–cell adhesion molecule that plays a role in breast cancer metastasis. Here, we show that in vivo expression of N-cadherin in the PyMT mouse model, which enhances mammary tumor metastasis, res...
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Article
Effects of Herbicides on Lemna gibba and Recovery from Damage After Prolonged Exposure
To determine the potential impact of contaminants on the aquatic vascular plants Lemna sp., toxicity tests are usually conducted for a 4- to 14-day exposure, and the toxicity is usually expressed as EC50. However...
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Article
Recovery of Lemna sp. after Exposure to Sulfonylurea Herbicides
No abstract available.
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Article
Comparative Sensitivity of Pseudokirchnetiella subcapitata vs. Lemna sp. to Eight Sulfonylurea Herbicides
No abstract available.
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Chapter and Conference Paper
Surgical treatment of unruptured cerebral aneurysms in the elderly
We retrospectively analyzed the prevalence and surgical outcomes of unruptured cerebral aneurysms in the elderly for the past five years. Between 1998 and 2002, we collected data from 575 subjects with unruptu...
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Article
Impact of biochemical failure on long-term clinical outcome after radical prostatectomy for prostate cancer in Japan
Detailed information is needed to understand the impact of biochemical failure (bF) on long-term outcome after definitive therapy for prostate cancer. In all, 223 consecutive men treated with radical retropubi...
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Chapter and Conference Paper
Inappropriate Defibrillator Therapies: Do Dual-chamber Devices Really Provide a Remedy?
Inappropriate shock therapy from an implantable cardioverter defibrillator (ICD) is very painful for patients and may lead to a poor quality of life (QOL) and/or proarrhythmic effects. Excessively aggressive a...
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Article
Changes in prostate-specific antigen and hormone levels following withdrawal of prolonged androgen ablation for prostate cancer
We conducted a study in order to characterize changes after withdrawal of androgen ablation (AA) for prostate cancer. AA was withdrawn in 38 Japanese patients with prostate cancer who had undergone this therap...
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Article
Probability of prostate cancer at various levels of per cent free prostate specific antigen in Japanese men with total PSA of 4.1-10.0 ng/ml
Estimates for the likelihood of prostate cancer at different levels of per cent free prostate specific antigen (PSA) were derived from experience with consecutive Japanese male patients with intermediate total...
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Article
High-performance liquid chromatographic quantification of allysine as bis-p-cresol derivative in elastin
The first step in normal cross-linking in elastin is the formation of α-aminoadipic-δ-semialdehyde, allysine, through oxidative deamination of specific peptidyl lysine by the enzyme lysyl oxidase (EC 1.4.3.13). ...
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Chapter
Analysis of Xanthomonas campestris pv. glycines from Soybean Using Simple Serological Procedures
Soybean bacterial pustule, caused by X. campestris pv. glycines (Xcg), can affect soybean at any stage of plant growth. Symptom is restricted to leaves and consisted of small yellow to brown lesions with red pust...
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Article
Biological action of keratinocyte growth factor in BeWo cells, a human choriocarcinoma cell line
Previously, we reported that the expression of keratinocyte growth factor (KGF) is enhanced in secretory phase endometrial and decidual cells in early pregnancy as compared with the expression of KGF in prolif...
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Article
Risk of progression and dying of clinically localized prostate cancer in Japan
Study was made of the conservative management of 107 men with clinically localized prostate cancer. Distant metastasis developed more frequently in patients with poorly differentiated tumors than in those with...
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Article
Transforming growth factor-α, like epidermal growth factor, stimulates cell proliferation and inhibits prolactin secretion in the human decidual cells in vitro
In order to clarify the biological action of transforming growth factor alpha (TGF-α) in the human decidua, we investigated the effects of TGF-α on cell proliferation and prolactin (PRL) secretion in cultured ...
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Chapter
4-Chloro-3-Hydroxyanthranilate Attenuate Quinolinic Acid Accumulation in Brain Following Transient Cerebral Ischemia in the Gerbil
The kynurenine pathway is the predominant route of L-tryptophan metabolism in most tissues. Two aspects of L-tryptophan catabolism through this pathway are of particular interest. Firstly, the initial enzyme o...
