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Chapter
The Effect of Prostacyclin Analogs on Vascular K Channels
Drugs such as pinacidil, nicorandil, minoxidil sulphate and cromakalim effect vasodilatation by membrane hyperpolarization of the vascular smooth muscle cells, which in some tissues raises the membrane potenti...
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Chapter
Effects of garlic on the electro-mechanical properties in the canine carotid artery
In isolated strips of canine carotid arteries, aqueous garlic extract (from 0.2 to 200 g powder/l) and ajoene (10−6to 10−3mol/l) affected membrane potential and tension. A gradual increase of the effector concent...
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Article
NMR Studies of Cation Induced Conformational Changes in Anionic Biopolymers at the Endothelium-Blood Interface
In the vessel walls, the connective tissue components surrounding the smooth muscle cells display a high binding capacity for small cations which has been ascribed to the presence of polyanionic proteoglycans. 23
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Chapter
Ventilatory and Blood Pressure Reactions to Acute Hypoxia and Hyperoxia in Chemoreceptor-Denervated NWR and SHR
The peripheral arterial chemoreceptors are the specific sensors that inform the central nervous system about the arterial oxygen tension or content. They play an important role not only in the reflex control o...
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Chapter
Effects of Chronic Chemoreceptor Stimulation on Blood Pressure and Blood Volume in Spontaneously Hypertensive Rats (SHR)
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Almitrine at a dose of 1.0 mg/kg/d given orally over 14 weeks lowers the plasma volume in both carotid sinus nerve tran...
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Chapter
Effects of Hyperoxia on Salt Intake in Carotid Body Denervated Spontaneously Hypertensive Rats (SHR)
The factors controlling the excessive salt appetite of SHR are not entirely understood. Various environmental factors and humoral systems have been postulated to contribute to this appetite (Denton, 1984; Freg...
