Page
%P
-
Article
Open AccessIRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV
CD8+ T-cell functions are critical for preventing chronic viral infections by eliminating infected cells. For healthy immune responses, beneficial destruction of infected cells must be balanced against immunopath...
-
Article
Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy
Autophagy is a lysosomal degradation pathway important for cellular homeostasis, mammalian development, cancer and immunity. Many molecular components of autophagy have been identified, but little is known abo...