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  1. No Access

    Article

    A phosphorylation site mutant of Schizosaccharomyces pombe cdc2p fails to promote the metaphase to anaphase transition

    The protein kinase cdc2p is a key regulator of the G1-S and G2-M cell cycle transitions in the yeast Schizosaccharomyces pombe. Activation of cdc2p is regulated by its phosphorylation state and by interaction wi...

    K. L. Gould, A. Feoktistova, U. Fleig in Molecular and General Genetics MGG (1998)

  2. No Access

    Article

    A wat1 mutant of fission yeast is defective in cell morphology

    The organization of the actin cytoskeleton plays an integral role in cell morphogenesis of all eukaryotes. We have isolated a temperature-sensitive mutant in Schizosaccharomyces pombe, wat1-1, in which acting pa...

    J. T. Kemp, M. K. Balasubramanian, K. L. Gould in Molecular and General Genetics MGG (1997)

  3. No Access

    Article

    Novel alleles ofcdc13 andcdc2 isolated as suppressors of mitotic catastrophe inSchizosaccharomyces pombe

    Cell cycle control in the fission yeastSchizosaccharomyces pombe involves interplay amongst a number of regulatory molecules, including thecdc2, cdc13, cdc25, weel, andmik1 gene products. Cdc2, Cdc13, and Cdc25 a...

    L. D. Berry, K. L. Gould in Molecular and General Genetics MGG (1996)

  4. No Access

    Chapter and Conference Paper

    The Poststenotic Vessel Segment during Dynamic Exercise: Effect of Oral Isosorbide-dinitrate

    Coronary vasomotion of normal, stenotic, and poststenotic vessel segments was studied in 18 patients with coronary artery disease at rest, during submaximal bicycle exercise, and 5 min after sublingual nitrogl...

    A. Gaglione, Otto M. Hess M.D., C. Haemmerli… in Adrenergic Mechanisms in Myocardial Ischem… (1991)

  5. No Access

    Chapter

    Opposite ends of the intervention spectrum: Effects of intracoronary thrombolysis on long-term survival and LV function — Detection of early CAD by non-invasive positron imaging

    In kee** with the theme of this conference, we report on the opposite ends of the spectrum involving intervention therapy for coronary artery disease. At the invasive end, we present our data on the effects ...

    K. L. Gould, R. W. Smalling, N. Mullani… in Improvement of Myocardial Perfusion (1985)

  6. No Access

    Chapter and Conference Paper

    Noninvasive Detection of 47% Diameter Coronary Stenosis by Myocardial Emission Computed Tomography of Nitrogen-13 Ammonia During Pharmacologic Coronary Vasodilation in Intact Dogs

    Coronary atherosclerosis often first presents as sudden death or myocardial infarction after a clinically silent period of progressing anatomic disease. Since atherosclerosis may be reversible [1–3], a routine...

    K. L. Gould, H. R. Schelbert, M. E. Phelps, E. J. Hoffman in Frontiers in Nuclear Medicine (1980)

  7. No Access

    Chapter

    Intra-arterial pressure

    The force of cardiac contraction is transmitted to the arterial system as pressure which maintains patency of blood vessels and perfusion of capillaries. The term pressure is derived from the Latin verb, preme...

    K. L. Gould in Methods in Angiology (1980)