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Article
Geoneutrinos and geoscience: an intriguing joint-venture
The review is conceived to provide a useful toolbox to understand present geoneutrino results with a view to shed light on Earth’s energetics and composition. The status of the geoneutrino field is presented s...
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Article
Recent Results and Future Prospects of Kaonic Nuclei at J-PARC
\({\bar{K}}\) K ...
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Article
Open AccessUsing a quality of life (QoL)-monitor: preliminary results of a randomized trial in Dutch patients with early breast cancer
The diagnosis and treatment of cancer negatively affect patients’ physical, functional and psychological wellbeing. Patients’ needs for care cannot be addressed unless they are recognized by healthcare provide...
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Article
Effect of increasing pressure on the structure and temperature-induced changes in magnetic properties of heterospin complexes
The study is concerned with structural rearrangements in the crystals of heterospin complexes Cu(hfac)2 with nitroxide radicals LR (hfac is hexafluoroacetylacetonate, LR is 2-(1-R-1H-pyrazol-4-yl)-4,4,5,5-tetrame...
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Chapter
Spatial Distribution of Strength—Comparison Between Indian and Japanese Embankments
The spatial distribution of N value inside the earth-fill dams and river dikes are identified by the sounding tests, and compared between in Japan and in India. In this research, the Swedish Weight Sounding (SWS)...
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Article
Open AccessSimultaneous measurement of p53:Mdm2 and p53:Mdm4 protein-protein interactions in whole cells using fluorescence labelled foci
In this report we describe the development of a Fluorescent Protein-Protein Interaction-visualization (FLUOPPI) to enable the simultaneous measurement of both Mdm2:p53 and Mdm4:p53 interactions in order to assess...
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Article
Distribution of uranium in Japanese river waters determined with inductively coupled plasma mass spectrometry
The uranium concentration in some selected Japanese river waters after Fukushima Daiichi Nuclear Power Plant (FDNPP) accident was measured using inductively coupled plasma mass spectrometry (ICP-MS). We report...
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Article
Open AccessEfficacy and safety of trastuzumab, lapatinib, and paclitaxel neoadjuvant treatment with or without prolonged exposure to anti-HER2 therapy, and with or without hormone therapy for HER2-positive primary breast cancer: a randomised, five-arm, multicentre, open-label phase II trial
Dual blockade of HER2 promises increased pathological complete response (pCR) rate compared with single blockade in the presence of chemotherapy for HER2-positive (+) primary breast cancer. Many questions rema...
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Article
Open AccessCross-cultural comparison of breast cancer patients’ Quality of Life in the Netherlands and Japan
Cultural differences are hypothesized to influence patients’ Quality of Life (QoL) reports. However, there is a lack of empirical cross-cultural studies comparing QoL of patients with cancer. This study aims t...
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Article
Influence of ABCB1 and ABCG2 polymorphisms on the antiemetic efficacy in patients with cancer receiving cisplatin-based chemotherapy: a TRIPLE pharmacogenomics study
Resistance to antiemetic treatment with 5-hydroxytryptamine-3 receptor antagonist is an issue. This study evaluated the potential roles of ABCB1 and ABCG2 polymorphisms in antiemetic treatment resistance in patie...
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Article
Validation of the distress and impact thermometer and the changes of mood during the first 6 months of treatment in gynecological cancer patients: a Kansai Clinical Oncology Group (KCOG)-G1103 prospective study
To verify distress and impact thermometer (DIT) for screening emotional distress in gynecological cancer patients by Hospital Anxiety and Depression Scale total (HADS-T) as gold standard and to assess emotiona...
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Article
Atom probe tomography of nanoscale electronic materials
As the characteristic length scale of electronic devices shrinks, so does the required scale for measurement techniques to provide useful feedback during development and fabrication. The current capabilities o...
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Article
[18F]DPA-714 PET imaging of translocator protein TSPO (18 kDa) in the normal and excitotoxically-lesioned nonhuman primate brain
We aimed to characterize pharmacologically the TSPO- radioligand [18F]DPA-714 in the brain of healthy cynomolgus monkeys and evaluate the cellular origin of its binding in a model of neurodegeneration induced by ...
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Article
Open AccessImpact of intra-arterial chemotherapy including internal carotid artery for advanced paranasal sinus cancers involving the skull base
The most significant problem of intra-arterial chemotherapy for advanced paranasal sinus carcinomas and residual cancers supplied by internal carotid artery (ICA) and involving the skull base is the lack of sa...
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Article
Safety of polypropylene mesh for incarcerated groin and obturator hernias: a retrospective study of 110 patients
The purpose of this study was to evaluate the mesh repair for an incarcerated groin hernia.
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Article
How to best measure atomic segregation to grain boundaries by analytical transmission electron microscopy
This study provides an overview of the recent experiments employing methods that analyse, systematically, series of analytical spectra acquired either in nanobeam mode in a transmission electron microscope or ...
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Article
Phylogeographic and population genetic analyses reveal Pleistocene isolation followed by high gene flow in a wide ranging, but endangered, freshwater mussel
Freshwater organisms of North America have had their contemporary genetic structure shaped by vicariant events, especially Pleistocene glaciations. Life history traits promoting dispersal and gene flow continu...
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Article
Open AccessIdentification of serum miRNAs as novel non-invasive biomarkers for detection of high risk for early gastric cancer
Many micro-RNAs (miRNAs) are differentially expressed in Helicobacter pylori-infected gastric mucosa and in gastric cancer tissue and previous reports have suggested the possibility of serum miRNAs as complementa...
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Article
A Search for Deeply Bound Kaonic Nuclear States at J-PARC
The J-PARC E15 experiment has the aims to search for the simplest kaonic nuclear bound state, K − pp, by the in-flight 3He(K −,n) reaction. The exclusive measuremen...
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Article
Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer
Our recent study showed critical roles of Dmp1 as a sensor of oncogenic Ras, HER2/neu signaling and activation of the Arf-p53 pathway. To elucidate the role of human DMP1 (hDMP1) in breast cancer, one hundred ...
